DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and Bmp1

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_112613.1	Gene:	Bmp1 / 83470	RGDID:	620739	Length:	990	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	95/329 - (28%)
Similarity:	141/329 - (42%)	Gaps:	67/329 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLLLIIL-----GISLGD-SMPLEDMDSQEMIDLTD-------LGDTLFGNPD-----VETTGAL 57
            ||||::|     .:.|.| :..|.:.|:.|:::..|       |||......|     |:....|
  Rat    16 LLLLLLLPRAGRPLDLADYTYDLGEEDAPELLNYKDPCKAAAFLGDIALDEEDLRAFRVQQAAVL 80

  Fly    58 ---------VEALGVESPLNPEEL-GTYHEGDILIPLSYRDARFNGTRNGILALSSR----WPGG 108
                     ::|.|..|.|..:.. |....|.        ..|:........|.:||    ||.|
  Rat    81 RQQTAQRSSIKAAGNSSALGRQSTSGQPQRGS--------RGRWRSRPRSRRAATSRPERVWPDG 137

  Fly   109 VVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEV 173
            |:|:.|.|.||..:......|.:.:...|||.|..||.|..||.......||.|.:||.||..:.
  Rat   138 VIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQA 202

  Fly   174 NLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGV 238
            .....||.: :|..:|||.|.:||:||..|.:||.:|.::::||:|....||.|...:.....|.
  Rat   203 ISIGKNCDK-FGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGE 266

  Fly   239 EYDYGSVMHYSPTSFTR-------------NG-QPTLKALRATSDASQMGQRKGFSAGDVRKINA 289
            .||:.|:|||:..:|:|             || :|::            |||...|.||:.:...
  Rat   267 TYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSI------------GQRTRLSKGDIAQARK 319

  Fly   290 MYKC 293
            :|||
  Rat   320 LYKC 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	69/208 (33%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	63/197 (32%)
Bmp1	NP_112613.1	ZnMc_BMP1_TLD	125..324	CDD:239808	71/212 (33%)
		Astacin	132..325	CDD:279708	68/205 (33%)
		CUB	326..435	CDD:278839
		CUB	439..548	CDD:278839
		FXa_inhibition	559..591	CDD:291342
		CUB	595..704	CDD:278839
		FXa_inhibition	711..746	CDD:291342
		CUB	751..860	CDD:278839
		CUB	864..977	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810