DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and Tll1

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001099551.1	Gene:	Tll1 / 678743	RGDID:	1306120	Length:	1013	Species:	Rattus norvegicus

Alignment Length:	203	Identity:	71/203 - (34%)
Similarity:	108/203 - (53%)	Gaps:	13/203 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ALSSR----WPGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTTEKDYISIGSGKSGC 160
            |.:||    |||||:||.|.|.||..:......|.:.:...|||.|..|:.|:.||.......||
  Rat   148 AATSRTERIWPGGVIPYVIGGNFTGSQRAMFKQAMRHWEKHTCVTFTERSDEESYIVFTYRPCGC 212

  Fly   161 WSSIGRLG-GRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVN 224
            .|.:||.| |.|.::: ..||.: :|..:|||.|.:||:||..|.:||::|.::::||:|....|
  Rat   213 CSYVGRRGNGPQAISI-GKNCDK-FGIVVHELGHVIGFWHEHTRPDRDNHVTIIRENIQPGQEYN 275

  Fly   225 FEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKALRATSDAS----QMGQRKGFSAGDVR 285
            |.|.........|..||:.|:|||:..:|:|.  ..|..:..:.|.:    .:|||...|.||:.
  Rat   276 FLKMEPGEVNSLGERYDFDSIMHYARNTFSRG--MFLDTILPSRDDNGIRPAIGQRTRLSKGDIA 338

  Fly   286 KINAMYKC 293
            :...:|:|
  Rat   339 QARKLYRC 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	69/199 (35%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	64/188 (34%)
Tll1	NP_001099551.1	ZnMc_BMP1_TLD	148..347	CDD:239808	71/203 (35%)
		Astacin	155..348	CDD:279708	68/196 (35%)
		CUB	349..458	CDD:278839
		CUB	462..571	CDD:278839
		FXa_inhibition	582..614	CDD:291342
		CUB	618..727	CDD:278839
		FXa_inhibition	734..769	CDD:291342
		CUB	774..883	CDD:278839
		CUB	887..1000	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810