DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and hce2l1

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_009302797.1	Gene:	hce2l1 / 564183	ZFINID:	ZDB-GENE-070912-147	Length:	232	Species:	Danio rerio

Alignment Length:	224	Identity:	87/224 - (38%)
Similarity:	119/224 - (53%)	Gaps:	23/224 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 EGDILIPLSYRDARFNGTRNGILAL--SSRWPGGV-----VPYEIKGPFTSQELGNINHAFKEYH 134
            |||||.|         |:|:.|..|  |.|||..|     |||.:...:...:...|.....:..
Zfish    21 EGDILSP---------GSRSAITCLGDSCRWPKAVDGFVYVPYIMSTLYDDMDRITIETGMLDIS 76

  Fly   135 TKTCVRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFH 199
            :.|||:|.|||.:.::::| ..:.||||.:|..||.|.|:||||.|:.: |...|||||||||.|
Zfish    77 SSTCVKFVPRTHQANFLNI-QPRYGCWSYLGMTGGSQTVSLQSPGCMWS-GVASHELMHALGFVH 139

  Fly   200 EQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKAL 264
            ||:|.:||.||.::.:||......||.|..:.   .....|||.|||||...:|:.:|.||:  :
Zfish   140 EQSRSDRDRYVSILWENIIENQRHNFRKYETN---NLNTAYDYSSVMHYGRYAFSEDGGPTI--I 199

  Fly   265 RATSDASQMGQRKGFSAGDVRKINAMYKC 293
            ........:|||.|.|..|:.|||.:|.|
Zfish   200 PKPDPYIPIGQRDGPSILDIHKINILYNC 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	76/195 (39%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	71/188 (38%)
hce2l1	XP_009302797.1	Astacin	41..229	CDD:279708	76/195 (39%)
hce2l1	XP_009302797.1	ZnMc_hatching_enzyme	47..228	CDD:239810	71/187 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	165	1.000	Domainoid score	I3861
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	167	1.000	Inparanoid score	I4142
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	1	1.000	-	-		mtm6586
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	9.070