DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and cuzd1.2

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_021323075.1	Gene:	cuzd1.2 / 555768	ZFINID:	ZDB-GENE-131119-30	Length:	718	Species:	Danio rerio

Alignment Length:	164	Identity:	39/164 - (23%)
Similarity:	66/164 - (40%)	Gaps:	47/164 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 ELGNI---NHAFKEYHTKTCVRFKPRTTEKDYISIGSG-KSGCWSSIGRLGGRQEVNLQSPNCL- 181
            :|||:   :...:.:|:.:  |:.......|:..:..| |:...||:....||  |:..|.|.:
Zfish   397 QLGNVCFNDTTHQAFHSTS--RYLTVVFRSDFSGVSHGFKAHFTSSLTADQGR--VDCSSDNMVI 457

  Fly   182 ---RTYGTPIHELMHALGFFHEQNRHERDSYV--RVMKDNI-KPEMMVNFEKSSSRTQYGFGVEY 240
               |:|       :::|||      ...|.||  |:.:.|| ..|::..|..::..|
Zfish   458 VLRRSY-------LNSLGF------SGNDLYVDDRLCRPNISSTEVVFRFPLNTCGT-------- 501

  Fly   241 DYGSVMHYSPTSFTRNGQPTLKALRATSDASQMG 274
              ...|..|..|:|.|       :||:  .||.|
Zfish   502 --AKKMMNSFVSYTNN-------VRAS--PSQSG 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	39/164 (24%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	39/164 (24%)
cuzd1.2	XP_021323075.1	CUB	21..127	CDD:238001
		Somatomedin_B	131..164	CDD:307259
		Somatomedin_B	175..214	CDD:321959
		Somatomedin_B	<239..260	CDD:307259
		CUB	330..439	CDD:238001	8/43 (19%)
		ZP	450..694	CDD:214579	26/107 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900