DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5715 and mep1a.1

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001025452.1	Gene:	mep1a.1 / 553530	ZFINID:	ZDB-GENE-041001-209	Length:	598	Species:	Danio rerio

Alignment Length:	224	Identity:	79/224 - (35%)
Similarity:	110/224 - (49%)	Gaps:	27/224 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 EGDILIPLSYRDARFNGTRNGILALSSRW--PGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCV 139
            ||||.:|..         |.|::..:.||  |   :||.:.........|.|..||:.|..|:||
Zfish    48 EGDIALPPG---------RIGLINTTYRWKFP---IPYILSDSLDLNAKGAIYQAFEVYRLKSCV 100

  Fly   140 RFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPI-HELMHALGFFHEQNR 203
            .|||...||.||....| .||||.:|.....|.::| .|.|  .:...| |||:|||||:|.|:|
Zfish   101 DFKPYEGEKTYIKFEKG-DGCWSFVGDQQNGQVLSL-GPGC--DHKAVIEHELLHALGFYHMQSR 161

  Fly   204 HERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKALRATS 268
            .:||.||::..|.:...:..||.|............|||.|||||.|.:|  |..|::..:  |:
Zfish   162 QDRDDYVKIWLDQVIEGLEHNFNKYDDSFVTDLNTPYDYESVMHYRPFAF--NKDPSIPTI--TT 222

  Fly   269 DASQ----MGQRKGFSAGDVRKINAMYKC 293
            :..:    :||...||..|:.::|.||.|
Zfish   223 NIPEFYKIIGQYLDFSEMDIVRLNRMYNC 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	72/197 (37%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	66/188 (35%)
mep1a.1	NP_001025452.1	ZnMc	26..251	CDD:294052	78/222 (35%)
		Astacin	65..253	CDD:279708	72/198 (36%)
		MAM	261..420	CDD:279023
		MAM	261..419	CDD:99706
		MATH	419..582	CDD:295307
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25214
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.010