DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and tll2l

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001016661.1	Gene:	tll2l / 549415	XenbaseID:	XB-GENE-478930	Length:	500	Species:	Xenopus tropicalis

Alignment Length:	288	Identity:	99/288 - (34%)
Similarity:	149/288 - (51%)	Gaps:	32/288 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LIILGISLGDSMPLEDMDSQEMIDLTDLGDTLFGNPDVETTGALVEALGVESPLNPEELGTYHEG 78
            :||..::...|:||..:  ::.::..|..:|...|.....|..:....|::..|        .:|
Frog     9 IIICLVTYATSLPLTTL--EKPLESDDHQETHKPNDADIFTQIIASNEGIDQLL--------LQG 63

  Fly    79 DILIPLSYRDARFNGTRNGILALSSRWP----GGV-VPYEIKGPFTSQELGNINHAFKEYHTKTC 138
            ||.|.:         .|:.:...:.:|.    |.| ||:.:...:|..:|..|..|.:|:.|.||
Frog    64 DIAIRV---------VRSSLQCDNCKWDISSNGKVPVPFTVSPGYTKSQLALITAAMQEFETLTC 119

  Fly   139 VRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNR 203
            |.|.|:|.||:.|:|.:| :||||.|||.||.|:|:|...:|: ..|...|||.|.|||.||..|
Frog   120 VDFVPKTNEKNVININNG-NGCWSYIGRSGGVQQVSLSKQSCM-VKGIIQHELNHVLGFVHEHVR 182

  Fly   204 HERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKALRATS 268
            .:||.||.|:|.||.|:.:.||:.:.:.   ..|:.|||.|||||...:|:.:  |.|..|....
Frog   183 SDRDQYVNVVKKNILPDSLGNFDIAVTN---NLGLPYDYYSVMHYPRNAFSIS--PFLPTLITKP 242

  Fly   269 DAS-QMGQRKGFSAGDVRKINAMYKCKV 295
            |.: |:|||.|.:..|:.|||.:|.|.|
Frog   243 DPTIQIGQRYGLTNLDIAKINKLYNCDV 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	82/196 (42%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	79/185 (43%)
tll2l	NP_001016661.1	ZnMc_hatching_enzyme	86..268	CDD:239810	80/188 (43%)
		CUB	272..382	CDD:238001
		CUB	385..495	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.070