Protein Alignment CG5715 and ASTL

DIOPT Version :9

• Sequence 1: NP_651242.1
• Gene: CG5715 / 42895
• FlyBaseID: FBgn0039180
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: XP_011509507.1
• Gene: ASTL / 431705
• HGNCID: 31704
• Length: 436
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 104/295 - (35%)
• Similarity: 142/295 - (48%)
• Gaps: 49/295 - (16%)

  Fly    15 IILGISL--------GDSMPLEDMDSQEMIDLTDLGDTLFGNPDVE--TTGALVEALGVESPLNP 69
            :|||..|        |.|.|    |.     ||..|....|:.|:.  ..|.::|    |:|
Human    25 VILGAPLASSCAGACGTSFP----DG-----LTPEGTQASGDKDIPAINQGLILE----ETP--- 73

  Fly    70 EELGTYHEGDILIPLSYRDARFNGTRNGILALSSRWPGG-----VVPYEIKGPFTSQELGNINHA 129
             |.....||||:.|..:|         .:.|.|::||.|     .||:.:...:.......|..|
Human    74 -ESSFLIEGDIIRPSPFR---------LLSATSNKWPMGGSGVVEVPFLLSSKYDEPSRQVILEA 128

  Fly   130 FKEYHTKTCVRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCL-RTYGTPIHELMH 193
            ..|:...||:||.....::|:||| ....||:||:||.||.|.|:| :|.|| :..|..:|||||
Human   129 LAEFERSTCIRFVTYQDQRDFISI-IPMYGCFSSVGRSGGMQVVSL-APTCLQKGRGIVLHELMH 191

  Fly   194 ALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQ 258
            .|||:||..|.:||.|:||..:.|.|...:||.||.|....   ..|||.|||||...:|:|.|.
Human   192 VLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKSQSSNML---TPYDYSSVMHYGRLAFSRRGL 253

  Fly   259 PTLKALRATSDASQMGQRKGFSAGDVRKINAMYKC 293
            ||:..|.|.|  ..:|||...||.|:.::..:|.|
Human   254 PTITPLWAPS--VHIGQRWNLSASDITRVLKLYGC 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	78/196 (40%)
		ZnMc_astacin_like	107..291	CDD:239807	74/189 (39%)
ASTL	XP_011509507.1	Astacin	97..288	CDD:279708	78/197 (40%)
		ZnMc	105..286	CDD:294052	74/187 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H128191
Inparanoid	1	1.050	145	1.000	Inparanoid score	I4437
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	1	1.000	-	-		otm41174
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2664
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.930