DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and tok

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001287510.1	Gene:	tok / 42944	FlyBaseID:	FBgn0004885	Length:	1464	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	70/217 - (32%)
Similarity:	107/217 - (49%)	Gaps:	14/217 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 PLSYRDARFNGTRNGILALSSR-WPGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTT 146
            ||.:|.||      .:.|...| |..||:||||.|.|:.........|.:.:...||::|..|..
  Fly   512 PLRHRVAR------AVTAKKERIWDYGVIPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDP 570

  Fly   147 E--KDYISIGSGKSGCWSSIGRLG-GRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDS 208
            |  .:||.......||.|.:|:.| |.|.::: ..||.: :|..:|||.|.:||:||..|.:|:.
  Fly   571 EIHPNYIVFTVRSCGCCSFVGKRGNGPQAISI-GRNCDK-FGIVVHELGHVVGFWHEHTRPDREK 633

  Fly   209 YVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQ-PTLKALRATS-DAS 271
            :|.:..:||......||...|.......|:.|||.|:|||:..:|::... .|:..:.... ...
  Fly   634 HVVIEHNNIMKGQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRP 698

  Fly   272 QMGQRKGFSAGDVRKINAMYKC 293
            ::|||...|.||:.:.|.:|||
  Fly   699 EIGQRLRLSQGDIAQANLLYKC 720

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	64/196 (33%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	59/188 (31%)
tok	NP_001287510.1	ZnMc_BMP1_TLD	520..721	CDD:239808	65/203 (32%)
		Astacin	527..721	CDD:279708	64/196 (33%)
		CUB	723..836	CDD:294042
		CUB	840..951	CDD:278839
		FXa_inhibition	958..993	CDD:291342
		CUB	997..1111	CDD:278839
		FXa_inhibition	1118..1153	CDD:291342
		CUB	1158..1267	CDD:278839
		CUB	1271..1390	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840