DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and Nrx-1

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001262840.1	Gene:	Nrx-1 / 42646	FlyBaseID:	FBgn0038975	Length:	1847	Species:	Drosophila melanogaster

Alignment Length:	253	Identity:	46/253 - (18%)
Similarity:	87/253 - (34%)	Gaps:	77/253 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 DARFNGTRNGILALSSRWPGGVVPY--------------EIKGPFTSQELG-------NINHAFK 131
            |.|||..|.  ...|.:.|..||.|              .:...|.:...|       |..:.|:
  Fly    56 DLRFNKARR--RRRSEQVPPVVVEYRRSYRVLIVSALLVSLAASFVTLSAGFQLDGSQNSFYTFR 118

  Fly   132 EYHT--KTCVRFKPRTTEKDYISIGSGKSGCWSSI------GRLGGRQEVNLQSPNCLRTYGTPI 188
            :::|  ...:..:.:|.:.:.:.:.:...|.:...      |.|  |...||.....:.|.|..:
  Fly   119 KWYTGLNGTLELEFKTEQPNGLVLYTDDGGTYDFFELKLVEGAL--RLRYNLGGGAQIITVGREL 181

  Fly   189 HELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYS---- 249
            |:     |.:|:         |:|::::.:..::|:.......|:   |.|:.:|.....|
  Fly   182 HD-----GHWHK---------VQVLRNDEQTSLIVDGVSQQRSTK---GKEFQFGKFASNSDVYV 229

  Fly   250 ---PTSFTRN----------GQPTLK-ALRATSDASQMG---------QRKGFSAGDV 284
               |..::..          .:|..: |:|....|.|.|         |::....|||
  Fly   230 GGMPNWYSSKLALLALPSVIFEPRFRGAIRNLVYADQPGGSTRRQEIKQQRDIKCGDV 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	40/237 (17%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	39/234 (17%)
Nrx-1	NP_001262840.1	LamG	110..263	CDD:238058	27/171 (16%)
		EGF_CA	311..347	CDD:238011
		Laminin_G_2	386..517	CDD:280389
		LamG	555..716	CDD:238058
		EGF	746..777	CDD:278437
		Laminin_G_2	814..945	CDD:280389
		LamG	988..1136	CDD:238058
		EGF	1164..1195	CDD:278437
		Laminin_G_2	1233..1356	CDD:280389
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444923
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930