DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and nas-39

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001360030.1	Gene:	nas-39 / 3565986	WormBaseID:	WBGene00003555	Length:	928	Species:	Caenorhabditis elegans

Alignment Length:	221	Identity:	74/221 - (33%)
Similarity:	110/221 - (49%)	Gaps:	10/221 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 GDILIPLSYRDARFNG--TRNGILALSSRWPGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVR 140
            ||:.....||:   ||  :|.........||.|::|:.|...|:.:.......|.:.:...|||.
Worm    31 GDVRFRRYYRN---NGRVSRAATAKKERIWPEGIIPFVIASNFSGEHQHLFLRAMRHWENFTCVS 92

  Fly   141 FKPRTT-EKDYISIGSGKSGCWSSIGRLG-GRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNR 203
            |.||.. .|.||:....|.||.|.:||.| |.|.::: ..||.: :|..:|||.|.:||:||..|
Worm    93 FVPRQPHHKHYITFTVDKCGCCSYVGRRGEGPQAISI-GKNCDK-FGIVVHELGHVVGFWHEHTR 155

  Fly   204 HERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNG-QPTLKALRAT 267
            .:||.||.:...:|:.....|||||........|..||:.|:|||:..:|:|.. ..|:.....:
Worm   156 PDRDMYVDIFYKSIQTGQDYNFEKSKPEEVDSLGEPYDFSSIMHYARDTFSRGAFYDTILPKPNS 220

  Fly   268 SDASQMGQRKGFSAGDVRKINAMYKC 293
            ....::|||...|.||:|:...:|||
Worm   221 GFRLEIGQRVQLSEGDIRQTKKLYKC 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	67/193 (35%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	62/186 (33%)
nas-39	NP_001360030.1	ZnMc_BMP1_TLD	48..247	CDD:239808	67/201 (33%)
		CUB	268..343	CDD:214483
		CUB	359..474	CDD:238001
		FXa_inhibition	480..515	CDD:373209
		CUB	519..622	CDD:366096
		FXa_inhibition	629..664	CDD:373209
		CUB	669..780	CDD:238001
		CUB	782..898	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810