DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and Mep1a

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_037275.1	Gene:	Mep1a / 25684	RGDID:	3080	Length:	748	Species:	Rattus norvegicus

Alignment Length:	221	Identity:	84/221 - (38%)
Similarity:	113/221 - (51%)	Gaps:	21/221 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 EGDILIPLSYRDARFNGTRNGILALSSRW--PGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCV 139
            :||||:|         .|||.:...||||  |   :||.:.........|.|.:||:.:..|:||
  Rat    57 QGDILLP---------RTRNALRDPSSRWKPP---IPYILADNLDLNAKGAILNAFEMFRLKSCV 109

  Fly   140 RFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPI-HELMHALGFFHEQNR 203
            .|||...|..|| |....|||||.:|.....|.::: ...|  .|...| ||::|||||||||:|
  Rat   110 DFKPYEGESSYI-IFQQFSGCWSMVGDQHVGQNISI-GEGC--DYKAIIEHEILHALGFFHEQSR 170

  Fly   204 HERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQ-PTLKALRAT 267
            .:||.||.:..:.|..:...||.....:|.......|||.|:|||.|.||.:|.. ||:......
  Rat   171 TDRDDYVNIWWNEIMTDYEHNFNTYDDKTITDLNTPYDYESLMHYGPFSFNKNETIPTITTKIPE 235

  Fly   268 SDASQMGQRKGFSAGDVRKINAMYKC 293
            .:|. :|||..|||.|:.::|.||.|
  Rat   236 FNAI-IGQRLDFSATDLTRLNRMYNC 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	74/194 (38%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	68/185 (37%)
Mep1a	NP_037275.1	ZnMc	32..260	CDD:294052	83/219 (38%)
		Astacin	75..261	CDD:279708	74/194 (38%)
		MAM	270..433	CDD:279023
		MAM	270..432	CDD:99706
		MATH	432..596	CDD:295307
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	641..668
		EGF	676..710	CDD:278437
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	149	1.000	Domainoid score	I4301
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46226
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.910