DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and nas-27

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_493926.2	Gene:	nas-27 / 188809	WormBaseID:	WBGene00003545	Length:	428	Species:	Caenorhabditis elegans

Alignment Length:	227	Identity:	69/227 - (30%)
Similarity:	104/227 - (45%)	Gaps:	16/227 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 LGTY-HEGDILIPLSYRDARFNGTRNGILALSSRW--PGGVVPYEIKGPFTSQELGNINHAFKEY 133
            :|.| ::|||.:      .:....|..|.....:|  |   :||.....|.|:....:..|.:.:
Worm    39 VGQYLYQGDIAV------VKSRARRAVIRQKHKKWKLP---MPYSFDRNFPSRSRQRVLEAMQFW 94

  Fly   134 HTKTCVRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQ-SPNCLRTYGTPIHELMHALGF 197
            ..||||.|........::||..| :||||.:|:....:|.:|. ..:|........||:.|.|||
Worm    95 SEKTCVTFHENRYVYPHVSIFEG-NGCWSFVGKQPSLREQSLSLERSCTDHTFVVAHEIAHTLGF 158

  Fly   198 FHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRN-GQPTL 261
            :||..|.:||.::.:...|:.|.:...|.|.|.:........|:||||||||...|..| .:|.:
Worm   159 YHEHARGDRDQFISIDYSNVNPNLTFAFAKESEKQLDHQEAAYEYGSVMHYSVDQFAVNTNRPVI 223

  Fly   262 KALRATSDASQMGQRKGFSAGDVRKINAMYKC 293
            .| |....|..||.|...:..||.::|.:|.|
Worm   224 YA-RDQKFAQAMGNRMRATFQDVSRMNVLYNC 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	62/194 (32%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	58/185 (31%)
nas-27	NP_493926.2	Astacin	65..254	CDD:279708	61/193 (32%)
		ZnMc_astacin_like	70..252	CDD:239807	59/186 (32%)
		CUB	334..410	CDD:294042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920