DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and nas-28

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_498342.3	Gene:	nas-28 / 185658	WormBaseID:	WBGene00003546	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	240	Identity:	69/240 - (28%)
Similarity:	117/240 - (48%)	Gaps:	23/240 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 EELGTY-HEGDIL--------IPLSYRDARFNGTRNGILALSSRWPGGV-VPYEIKGPFTSQELG 124
            :::..| .|.||:        |..:..:..:...|..|:..::.|...| :.|:.....::..:.
Worm    86 QDINEYTFESDIMLNEKQAKHIATAIENGNYRSKRQAIVDTTNFWSVSVPIFYQFDTKLSATNIA 150

  Fly   125 NINHAFKEYHTKTCVRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQ------SPNCLRT 183
            |:..|.:.::..:|:.||.....|:.:.:.|. .||||.:|:     :|::.      .||| .|
Worm   151 NVRKAIQFWNDNSCLSFKEDNNAKNRLFLSSA-GGCWSYVGK-----QVDMPYQMVSVGPNC-DT 208

  Fly   184 YGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHY 248
            :||..||||||:||:|:|:|.:||:||.|...||.|....||:|.:........:.|||||||.|
Worm   209 FGTATHELMHAIGFWHQQSRADRDNYVYVDFSNIIPSQAYNFQKMAVDQAQLLNLPYDYGSVMQY 273

  Fly   249 SPTSFTRNGQPTLKALRATSDASQMGQRKGFSAGDVRKINAMYKC 293
            .|.:|..:........:.....:.||||:..:..|:..:|.:|.|
Worm   274 YPYAFAVDSSKYTILAKENGFQNSMGQREAPAFSDIIGVNKLYNC 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	62/197 (31%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	59/190 (31%)
nas-28	NP_498342.3	Astacin	135..320	CDD:279708	60/191 (31%)
		ZnMc_astacin_like	135..316	CDD:239807	58/187 (31%)
		CUB	393..480	CDD:214483
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920