DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5715 and nas-13

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_510549.3	Gene:	nas-13 / 185492	WormBaseID:	WBGene00003532	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	259	Identity:	93/259 - (35%)
Similarity:	139/259 - (53%)	Gaps:	29/259 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 LGDTLFGNP-----DVETTGALVEALGVESPLNPEELGTYHEGDILIPLSYRDARFNGTRNGILA 100
            :.|:...||     |:..:|           ||...:.|:.....|..:      |...||.:..
Worm    67 VNDSAMYNPLRFEGDIANSG-----------LNSRSINTFFGDSPLFGI------FGVQRNAVRQ 114

  Fly   101 LSSRWPGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTT-EKDYISIGSGKSGCWSSI 164
            ...:|....:||.|...::|.....|..|.:||..|||:.|.|::. :.|||.| ....||:|.:
Worm   115 TYLKWEQARIPYTISSQYSSYSRSKIAEAIEEYRKKTCIDFSPKSAGDLDYIHI-VPDDGCYSLV 178

  Fly   165 GRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSS 229
            ||:||:|.|:| ...|::. |..|||||||:||||||:|.:||.||::...|::..:...|:|.|
Worm   179 GRIGGKQPVSL-GDGCIQK-GIIIHELMHAVGFFHEQSRADRDEYVKINWSNVEAGLQDQFDKYS 241

  Fly   230 SRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKALRATSDASQMGQRKGFSAGDVRKINAMYKC 293
            .......|.:|||||||||:||:|::||:||::.:...   .::|||.|||..|:.|||.:|.|
Worm   242 LNMIDHLGTKYDYGSVMHYAPTAFSKNGKPTIEPIEKN---VEIGQRAGFSENDIYKINMLYNC 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	81/191 (42%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	78/184 (42%)
nas-13	NP_510549.3	Astacin	118..304	CDD:279708	81/191 (42%)
		ZnMc_astacin_like	122..300	CDD:239807	78/183 (43%)
		ShK	367..404	CDD:279838
		ShK	414..450	CDD:279838
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I2268
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I2674
Isobase	1	0.950	-	0	Normalized mean entropy	S6346
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	1	1.000	-	-		mtm4854
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.880