DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5715 and nas-4

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001254938.1	Gene:	nas-4 / 182259	WormBaseID:	WBGene00003523	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	279	Identity:	106/279 - (37%)
Similarity:	154/279 - (55%)	Gaps:	28/279 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 MDSQEMIDL------TDLGDTLFGNP-----DVETTGALVEALGVESPLNPEELGTYHEGDILI- 82
            ::::::||.      |.|.|..|.:.     |::|.|..|:    :.|    .:|.|.|||||:
Worm    24 VNNKQVIDTSVPQTETTLNDADFHSDLHQRYDLQTLGIKVK----DDP----TIGNYSEGDILLE 80

  Fly    83 -PLSYRDARFNGTRNGILALSSRWPGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTT 146
             |..:.:......||.|..:..|||...:||.:...:.|.....|.:|..||||||||:|..|..
Worm    81 SPKKFVEENNKLGRNAIKQIYRRWPNNEIPYTLSSQYGSYARSVIANAMNEYHTKTCVKFVARDP 145

  Fly   147 EK--DYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSY 209
            .|  ||:.|...: ||:|.:|:.||:|.|:|.| .|::. ||.:||||||:||||||:|.:||||
Worm   146 SKHHDYLWIHPDE-GCYSLVGKTGGKQPVSLDS-GCIQV-GTIVHELMHAVGFFHEQSRQDRDSY 207

  Fly   210 VRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKALRATSDASQMG 274
            :.|:..|:.......|||.:..........|||.|:|||.|.:|:.:|:.||...::.|:  :||
Worm   208 IDVVWQNVMNGADDQFEKYNLNVISHLDEPYDYASIMHYGPYAFSGSGKKTLVPKKSGSE--RMG 270

  Fly   275 QRKGFSAGDVRKINAMYKC 293
            ||..||..||||||.:|.|
Worm   271 QRVKFSDIDVRKINKLYNC 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	84/192 (44%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	79/185 (43%)
nas-4	NP_001254938.1	Astacin	102..290	CDD:279708	84/193 (44%)
nas-4	NP_001254938.1	ZnMc_astacin_like	106..287	CDD:239807	79/185 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	170	1.000	Domainoid score	I2268
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I2674
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49330
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	1	1.000	-	-		mtm4854
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2664
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.010