DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and nas-37

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001024413.1	Gene:	nas-37 / 181208	WormBaseID:	WBGene00003553	Length:	765	Species:	Caenorhabditis elegans

Alignment Length:	275	Identity:	88/275 - (32%)
Similarity:	125/275 - (45%)	Gaps:	44/275 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 EDMDSQEMIDLTD------LGDTLFGNPDVETTGALVEALGVESPLNPEELGTYHEGDILIPLSY 86
            |:||.....|.|:      |.:.:|.| |:..|....|:|..||.               .|.|.
Worm    65 ENMDKSVKNDKTEATVNRKLWNEVFEN-DIILTLPQAESLLSESN---------------SPRSR 113

  Fly    87 RDARFNGTRNGILALSSRWPGGVVPYEI-KGPFTSQELGNINHAFKEYHTKTCVRFKPRTTEKDY 150
            |.|. ...||       .||...:.||. .|..|.::|  |..|.:......|.:||....::|.
Worm   114 RQAH-PDPRN-------FWPNLTISYEFYGGEETWRQL--IRSAIRHVEQNVCFKFKENGGDRDG 168

  Fly   151 ISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKD 215
            :....| :||||::||:||||.|:: ...| .:.|...||.:||||.:|||:|.:||:::.::.|
Worm   169 LRYYRG-NGCWSNVGRVGGRQLVSI-GYGC-DSLGIVSHETLHALGLWHEQSRDDRDNFISIVAD 230

  Fly   216 NIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRN-GQPTLKALRATSD---ASQMGQR 276
            .|......||.|.::......|..||.||||||...||..: ...|:|    |.|   .:.:|||
Worm   231 KITRGTEGNFAKRTAANSDNLGQPYDLGSVMHYGAKSFAYDWSSDTIK----TRDWRYQNTIGQR 291

  Fly   277 KGFSAGDVRKINAMY 291
            .|.|..|.:.||..|
Worm   292 DGLSFKDAKMINTRY 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	68/193 (35%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	65/188 (35%)
nas-37	NP_001024413.1	Astacin	122..309	CDD:279708	69/201 (34%)
		ZnMc_astacin_like	126..306	CDD:239807	65/188 (35%)
		CUB	370..455	CDD:214483
		TSP1	579..626	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020