DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5715 and nas-9

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_741532.1	Gene:	nas-9 / 178875	WormBaseID:	WBGene00003528	Length:	546	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	59/213 - (27%)
Similarity:	97/213 - (45%)	Gaps:	18/213 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 RNGILALSS---RW----PGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTTEK---- 148
            |:|:....|   :|    |   :.|.:.......:..:|..|..|....||:.|:...|.|
Worm   300 RSGVFFQESAVQKWDIWKP---IQYTLDDSLEESDKKDIRDALHEISINTCILFRYNATPKGYHL 361

  Fly   149 DYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVM 213
            :|:.:.|......|.:||......:.| |..|....|..:||.|||||..|:..|.:||.|:::.
Worm   362 NYMKVDSTTFCGLSYVGRTDPANPIYL-SFQCGDNRGVAMHETMHALGVSHQHLRLDRDKYIKID 425

  Fly   214 KDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRN-GQPTLKAL-RATSDASQMGQR 276
            ..||.|:....|..|.::....:|.:|.|.|:|||:.....:: .:||:..| ....:..::|||
Worm   426 WSNIDPQHYDTFAISDAKLYTSYGTKYAYDSIMHYNAYLGAKDPNKPTMIPLVNPQENTPKLGQR 490

  Fly   277 KGFSAGDVRKINAMYKCK 294
            ...:.||:|.:..|| |:
Worm   491 AKLTRGDIRLLKKMY-CR 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	56/201 (28%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	51/189 (27%)
nas-9	NP_741532.1	Astacin	311..505	CDD:279708	53/197 (27%)
		ZnMc_astacin_like	316..505	CDD:239807	52/192 (27%)
		ShKT	510..546	CDD:214586
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010