DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and nas-25

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_495880.1	Gene:	nas-25 / 174412	WormBaseID:	WBGene00003544	Length:	399	Species:	Caenorhabditis elegans

Alignment Length:	202	Identity:	75/202 - (37%)
Similarity:	99/202 - (49%)	Gaps:	20/202 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 LSSRWPGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTTEK-------DYISIGSGKS 158
            |:.|||...|||.: |..||....::..|.:|....||:||: ...||       ..:.:||
Worm    46 LTYRWPNNTVPYYV-GNVTSTIKKSVRLAIEELQAWTCIRFQ-NVNEKYSDGDSVRIVDLGS--- 105

  Fly   159 GCWSSIGRLG-GRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMM 222
             |.|.|||.. |.|:|:| :.||. ..||.|||||||:|..|.|:|.:|:.|:.::..||....:
Worm   106 -CSSPIGRQQIGTQDVSL-TKNCW-GMGTAIHELMHAIGIEHTQSRSDRNRYLDILAQNIDNRDL 167

  Fly   223 VNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKALRATSDASQMGQR-KGFSAGDVRK 286
            .|||..|.|..... |.||||||||||..||:..........:..|....||.. ..|.  |..:
Worm   168 PNFELLSPRLWANL-VPYDYGSVMHYSADSFSNKDDEQTMLPKDRSFIETMGSMIPNFY--DFDQ 229

  Fly   287 INAMYKC 293
            ||..|:|
Worm   230 INQYYQC 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	74/199 (37%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	69/192 (36%)
nas-25	NP_495880.1	Astacin	48..236	CDD:279708	73/198 (37%)
nas-25	NP_495880.1	ZnMc_astacin_like	52..234	CDD:239807	69/192 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920