DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and Mep1a

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_032611.2	Gene:	Mep1a / 17287	MGIID:	96963	Length:	760	Species:	Mus musculus

Alignment Length:	220	Identity:	84/220 - (38%)
Similarity:	110/220 - (50%)	Gaps:	19/220 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 EGDILIPLSYRDARFNGTRNGILALSSRW--PGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCV 139
            :||||:|         .|||.:...||||  |   :||.:.........|.|.|||:.:..|:||
Mouse    68 QGDILLP---------RTRNAMRDPSSRWKLP---IPYILADNLELNAKGAILHAFEMFRLKSCV 120

  Fly   140 RFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRH 204
            .|||...|..|| |....|||||.||.....|.::: ...| ....|..||::|||||||||:|.
Mouse   121 DFKPYEGESSYI-IFQKLSGCWSMIGDQQVGQNISI-GEGC-DFKATIEHEILHALGFFHEQSRT 182

  Fly   205 ERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQ-PTLKALRATS 268
            :||.||.:..|.|..:...||......|.......|||.|:|||.|.||.:|.. ||: ..:...
Mouse   183 DRDDYVNIWWDQIITDYEHNFNTYDDNTITDLNTPYDYESLMHYGPFSFNKNESIPTI-TTKIPE 246

  Fly   269 DASQMGQRKGFSAGDVRKINAMYKC 293
            ..:.:||...|||.|:.::|.||.|
Mouse   247 FNTIIGQLPDFSAIDLIRLNRMYNC 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	74/193 (38%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	68/184 (37%)
Mep1a	NP_032611.2	ZnMc	46..271	CDD:381785	83/218 (38%)
		MAM	281..444	CDD:366209
		MATH	443..607	CDD:351761
		EGF	688..722	CDD:333761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	149	1.000	Domainoid score	I4395
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8881
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.910