DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and nas-36

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_492109.2	Gene:	nas-36 / 172506	WormBaseID:	WBGene00003552	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	79/264 - (29%)
Similarity:	121/264 - (45%)	Gaps:	24/264 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 FGNPDVETTGALVEALGVESPLNPEELGTYHEGDILIPLSYRDA-------------RFNGTRNG 97
            ||:..||.:...|.....:..:|.:......||||.  ||.|.|             |..  |:.
Worm    68 FGHDAVEDSKKEVAISTQQGTINKKVSPFLFEGDIF--LSRRQAVDILKALSKDKTKRLR--RSF 128

  Fly    98 ILALSSRWPGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFK--PRTTEKDYISIGSGKSGC 160
            :...::.|....:.|..........:..|..|.:.:...||:.|:  ..:.:.|||...||: ||
Worm   129 VSDKTATWKTMPIKYRFHESIDFYTISQIIAAIRFWEDSTCITFENVSDSPDGDYIEFFSGQ-GC 192

  Fly   161 WSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNF 225
            :|.|||.||||.::: ..:|:: .|...||:.||||.:|||:|.:...||.:.:|.|.|..:.:|
Worm   193 YSMIGRNGGRQGISI-GESCVK-MGVIEHEIGHALGLWHEQSRPDALGYVTIERDFILPSYISDF 255

  Fly   226 EKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKALRATSDASQMGQRKGFSAGDVRKINAM 290
            .:...... ..|:.||.||||||..|:|:.:.:......|.:.....:|||:..|..||..||..
Worm   256 LQRDDEID-TLGIPYDLGSVMHYGSTAFSVDQKSKTVVTRDSLYQQTIGQREKLSFYDVATINTA 319

  Fly   291 YKCK 294
            | ||
Worm   320 Y-CK 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	63/193 (33%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	59/185 (32%)
nas-36	NP_492109.2	Astacin	134..323	CDD:279708	63/194 (32%)
		ZnMc_astacin_like	140..320	CDD:239807	59/183 (32%)
		CUB	380..478	CDD:214483
		TSP1	510..556	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820