DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and astl3a.3

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_031746774.1	Gene:	astl3a.3 / 100498584	XenbaseID:	XB-GENE-22069675	Length:	529	Species:	Xenopus tropicalis

Alignment Length:	312	Identity:	101/312 - (32%)
Similarity:	152/312 - (48%)	Gaps:	46/312 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LIILGISLGDS--------MPLEDMDSQEMIDLTDLGDTLFGNPDVETTGALVEALGVESPLNPE 70
            :|:|...:|.:        .|.::|..::.:...||.:.|..:.:.:.........|:|.|:..:
Frog     9 IILLACIMGSAWTYPAQIIFPYQEMLEKDSLTNLDLLEALGKSAEKDALATEGTVRGMEMPVLGK 73

  Fly    71 ELGTY-----------------HEGDILIPLSYRDARFNGTRNGILALSSRWPGG-----VVPYE 113
            :.|:.                 ::||||.|..         |:.:......||..     :|||.
Frog    74 KSGSVDVFTQISKVNRGIRVPTYQGDILRPKG---------RSAMNCTECLWPKSTDGTVIVPYN 129

  Fly   114 IKGPFTSQELGNINHAFKEYHTKTCVRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSP 178
            ....:::.:|.......:||.:.|||||.||..|.|::||.| .:||.|.:|::||.|.|.|.|.
Frog   130 FSSNYSADQLALFKSTMQEYESLTCVRFVPRANETDFLSIVS-DNGCASFLGKVGGDQTVQLDSY 193

  Fly   179 NCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYG 243
            .|:.. |...|||.|||||:|||:|.:||.||.:..:||.|....||.|:.|.   ..|:||||.
Frog   194 GCIYR-GIIQHELNHALGFYHEQSRSDRDDYVTIHTENIIPGYEGNFNKADSN---NLGLEYDYS 254

  Fly   244 SVMHYSPTSFTRNGQPTLKALRATSDASQMGQRKGFSAGDVRKINAMYKCKV 295
            ||||||..:|::||..|:  :........:|||.|.|..||.|||.:|:|.|
Frog   255 SVMHYSGDAFSKNGNLTI--VPKPDPTVPIGQRDGLSILDVSKINRLYQCDV 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	82/195 (42%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	78/188 (41%)
astl3a.3	XP_031746774.1	ZnMc_hatching_enzyme	121..302	CDD:239810	79/187 (42%)
		CUB	306..414	CDD:238001
		CUB	419..527	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.060