DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and accs

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_017948750.2	Gene:	accs / 100495810	XenbaseID:	XB-GENE-989873	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	92/253 - (36%)
Similarity:	126/253 - (49%)	Gaps:	41/253 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 NPEELGTYHE-------------------GDILIPLSYRDARFNGTRNGILALSSRWP----GGV 109
            |.|:...|||                   |||.|...         |:.....|..||    |.|
Frog    24 NYEDEEAYHEDVFSQILKSNNGTVKKLWQGDIAIETG---------RSATKCTSCLWPKSADGTV 79

  Fly   110 -VPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEV 173
             |||.:...::..|..:|..|..|::|.|||.|..|:||:|::.|.| .|||||||||.||.|.:
Frog    80 RVPYRLSADYSDNEKSSIRDALLEFNTLTCVHFVERSTEEDFLDIVS-DSGCWSSIGRTGGAQTL 143

  Fly   174 NLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGV 238
            :|.|..|| ..|...||:.|||||:|||:|.:||:|:.|:...|......:||...:.   ...:
Frog   144 SLMSSGCL-AKGIIQHEVDHALGFYHEQSRSDRDTYIDVLWQYICESDWGSFEMVDTD---NLDL 204

  Fly   239 EYDYGSVMHYSPTSFTR-NGQPTLKALRATSDASQMGQRKGFSAGDVRKINAMYKCKV 295
            .|||.|||||...:|:. :|||:|:.  .....:.:|||.|.|..||.|:..:|.||:
Frog   205 PYDYSSVMHYGWYAFSNTSGQPSLRP--KPDPTANIGQRYGLSPLDVSKVKELYGCKL 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	80/196 (41%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	76/185 (41%)
accs	XP_017948750.2	ZnMc	76..258	CDD:412141	77/188 (41%)
		CUB	261..374	CDD:238001	92/253 (36%)
		CUB	377..488	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2664
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.090