DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and astl2d.5

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_031756347.1	Gene:	astl2d.5 / 100495579	XenbaseID:	XB-GENE-22069752	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	219	Identity:	82/219 - (37%)
Similarity:	117/219 - (53%)	Gaps:	12/219 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 IPLSYRDARFNGTRNGILALSSRWP---GGV-VPYEIKGPFTSQELGNINHAFKEYHTKTCVRFK 142
            :|....|.....:|:.|......|.   |.| |||.:...:::.|:..:..|.:.|.|.|||:|.
Frog    56 VPRVQEDIAVGVSRSAITYTECLWQKTNGTVYVPYTLDDKYSNSEVNTMTSAMEVYATLTCVQFV 120

  Fly   143 PRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERD 207
            |.|.|.||::|.|| .||||.:||..|.|.|:::...| .:.||.:|||.|||||.|||:|.:||
Frog   121 PYTDEDDYVNITSG-DGCWSYMGRQRGAQVVSVEKGYC-TSEGTTMHELNHALGFVHEQSRSDRD 183

  Fly   208 SYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTR-NGQPTLKALRATSDAS 271
            :||.:|...|.|..:..|:|..|.   ..|..|||.|||||...:|:. .||.|:.|  ..:...
Frog   184 NYVNIMYQYISPGDVAEFKKMESN---NLGTTYDYRSVMHYPAWAFSNTTGQNTIVA--KPNPNI 243

  Fly   272 QMGQRKGFSAGDVRKINAMYKCKV 295
            .:|.....::.|:.|||.:|:|.|
Frog   244 IIGAGNTMTSLDIIKINRLYECDV 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	77/195 (39%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	74/185 (40%)
astl2d.5	XP_031756347.1	ZnMc	83..265	CDD:412141	75/188 (40%)
		CUB	268..377	CDD:395345	82/219 (37%)
		CUB	382..493	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010