DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and astl2f

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_002934133.3	Gene:	astl2f / 100495416	XenbaseID:	XB-GENE-22069764	Length:	624	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	100/286 - (34%)
Similarity:	135/286 - (47%)	Gaps:	46/286 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 ILGISLGDSMPLEDMDSQEMIDLTDLGDTLFGNPDVETTGALVEALGVESPLNPEELGTYHEGDI 80
            ::.:||.:... ||..|   ..|..|...|..|.|  |...||                  :|||
Frog   147 LMSLSLQEGQK-EDNSS---ASLDTLSQILEANKD--TNVPLV------------------QGDI 187

  Fly    81 LIPLSYRDARFNGTRNGILALSSRWPGGV-----VPYEIKGPFTSQELGNINHAFKEYHTKTCVR 140
            |..|.      ..|.|   ..|..||...     |||.|...|...|...|..|..|..|.:|:|
Frog   188 LEKLG------RSTTN---CTSCLWPRATSGLVNVPYTIASVFDDSEQELIQGALNELMTLSCIR 243

  Fly   141 FKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHE 205
            ||.||.|.|::|..|| :|||||:|:.||.|||::....|: ::|...||.:|||||.||..|.:
Frog   244 FKARTIETDFLSFQSG-NGCWSSVGKTGGSQEVSVSKSGCM-SHGIIQHETLHALGFIHEHCRSD 306

  Fly   206 RDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRN-GQPTLKALRATSD 269
            ||:||.::...|......:|.|.:|.   ..|::|||.|||||...:||.. ||.|:  :.....
Frog   307 RDNYVDIIYKYISEGDRSSFTKVNSN---NLGLQYDYSSVMHYGRFTFTNTPGQATI--IPKPDL 366

  Fly   270 ASQMGQRKGFSAGDVRKINAMYKCKV 295
            :..:|||.|.|:.||.|:|.:|.|.:
Frog   367 SVPIGQRYGVSSLDVAKLNKLYNCNI 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	79/196 (40%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	75/189 (40%)
astl2f	XP_002934133.3	ZnMc	209..390	CDD:412141	76/187 (41%)
		CUB	394..504	CDD:238001
		CUB	507..621	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.150