DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and astl2g

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_002934115.1	Gene:	astl2g / 100491886	XenbaseID:	XB-GENE-22069768	Length:	505	Species:	Xenopus tropicalis

Alignment Length:	225	Identity:	90/225 - (40%)
Similarity:	127/225 - (56%)	Gaps:	23/225 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 HEGDILIPLSYRDARFNG------TRNGILALSSRWPGGVVPYEIKGPFTSQELGNINHAFKEYH 134
            ||.||::.:.....:.:|      |.:||:.         |||.|...|::.|:..|..|.:::.
Frog    62 HESDIVVSVDRNAMKCDGDTCRWKTSDGIVR---------VPYTISANFSATEVSVIVDAMQDFA 117

  Fly   135 TKTCVRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFH 199
            |.|||.|.|||.|.||:.| ...|||||.:|:.||.|||:|....|:.. ||..|||.|||||:|
Frog   118 TLTCVNFVPRTVEPDYLQI-IPDSGCWSYVGKTGGAQEVSLNQGGCVGK-GTVQHELNHALGFYH 180

  Fly   200 EQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKAL 264
            ||:|.:||:||.::..||.|..:.||:|.::.   ..|.||||.|||||...:|.:  ||.|..:
Frog   181 EQSRSDRDNYVNILTGNIIPASIGNFDKYNTN---NLGQEYDYSSVMHYGRNAFAK--QPGLDTI 240

  Fly   265 RATSDAS-QMGQRKGFSAGDVRKINAMYKC 293
            ....:.: .:|||.|.|..|:.|||.:|:|
Frog   241 VPKPNPNVPIGQRYGLSNLDISKINQLYQC 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	82/191 (43%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	80/184 (43%)
astl2g	XP_002934115.1	Astacin	83..272	CDD:279708	85/204 (42%)
		ZnMc_hatching_enzyme	88..270	CDD:239810	83/197 (42%)
		CUB	270..384	CDD:238001	1/1 (100%)
		CUB	387..497	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4140
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9530
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.070