DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5715 and astl3b.4

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_031746772.1	Gene:	astl3b.4 / 100491283	XenbaseID:	XB-GENE-22069691	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	319	Identity:	112/319 - (35%)
Similarity:	153/319 - (47%)	Gaps:	62/319 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LIILGISLGDS--------MPLE---DMDSQEMIDLTD-LG-----DTL---------------F 46
            :|:|...:|.:        .|.:   |.||...:||.. ||     |.|               .
Frog     9 IILLACIMGSAWTYPAQIIFPYQEKLDKDSLTNLDLLKALGKSAEKDALATEGTVREMPVLGKKS 73

  Fly    47 GNPDVETTGALVEALGVESPLNPEELGTYHEGDILIPLSYRDARFNGTRNGILALSSRWPGG--- 108
            |:.||.|..:.|.. |:..|       || |||||.|..         |:.:......||..
Frog    74 GSVDVFTQISKVNR-GISVP-------TY-EGDILRPEG---------RSAMNCTECLWPKSTDG 120

  Fly   109 --VVPYEIKGPFTSQELGNINHAFKEYHTKTCVRFKPRTTEKDYISIGSGKSGCWSSIGRLGGRQ 171
              :|||.....:::.:|.....|.:||.:.|||||.||..|..:::|.|| |||.|.:|:|||.|
Frog   121 TVIVPYNFSSNYSADQLALFKSAMQEYESLTCVRFVPRANETAFLNIISG-SGCVSFLGKLGGAQ 184

  Fly   172 EVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHERDSYVRVMKDNIKPEMMVNFEKSSSRTQYGF 236
            .|.|.|..|:.. |...|||.|||||:|||:|.:||.||.:..:||.|....||.|:::.   ..
Frog   185 TVQLASYGCIYR-GIIQHELNHALGFYHEQSRSDRDDYVTIHTENILPGYEGNFNKANTN---NL 245

  Fly   237 GVEYDYGSVMHYSPTSFTRNGQPTLKALRATSDASQMGQRKGFSAGDVRKINAMYKCKV 295
            |:||||.|||||...:|::||..|:  :........:|||.|.|..||.|||.:|:|.|
Frog   246 GLEYDYSSVMHYPGDAFSKNGNLTI--VPKPDPTVPIGQRDGLSILDVSKINRLYQCDV 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	82/195 (42%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	78/188 (41%)
astl3b.4	XP_031746772.1	ZnMc_hatching_enzyme	119..300	CDD:239810	79/187 (42%)
		CUB	304..412	CDD:238001
		CUB	417..525	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010