DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5715 and mep1ba

DIOPT Version :9

Sequence 1:	NP_651242.1	Gene:	CG5715 / 42895	FlyBaseID:	FBgn0039180	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001070089.2	Gene:	mep1ba / 100151009	ZFINID:	ZDB-GENE-041014-209	Length:	677	Species:	Danio rerio

Alignment Length:	218	Identity:	89/218 - (40%)
Similarity:	119/218 - (54%)	Gaps:	13/218 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 EGDILIPLSYRDARFNGTRNGILALSSRWPGGVVPYEIKGPFTSQELGNINHAFKEYHTKTCVRF 141
            ||||||       ....:||.||....||| ..|||.:.........|.|..||::|..|||:.|
Zfish    53 EGDILI-------EEGESRNTILGEQYRWP-TTVPYFLDNSLEINAKGVILKAFEQYRLKTCIDF 109

  Fly   142 KPRTTEKDYISIGSGKSGCWSSIG-RLGGRQEVNLQSPNCLRTYGTPIHELMHALGFFHEQNRHE 205
            ||...|.:||.:..| |||:|.:| |..|:||:::.| || .:.||..||.:||||.:|||:|.:
Zfish   110 KPWNGESNYIFVFKG-SGCYSKVGNRQMGKQELSIGS-NC-DSLGTVEHEFLHALGLWHEQSRSD 171

  Fly   206 RDSYVRVMKDNIKPEMMVNFEKSSSRTQYGFGVEYDYGSVMHYSPTSFTRNGQPTLKALRATSDA 270
            ||.||.::.|.|:.....||...........||.|||.||||||.|||.:..:||: ..:.....
Zfish   172 RDDYVIIVWDQIQDGKEHNFNLYDETQSSSLGVPYDYSSVMHYSKTSFNKGSEPTI-VTKIPEFL 235

  Fly   271 SQMGQRKGFSAGDVRKINAMYKC 293
            :.:|||..||..|:.|:|.:|.|
Zfish   236 NVIGQRMEFSDNDLLKLNRLYNC 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5715	NP_651242.1	Astacin	104..295	CDD:279708	79/191 (41%)
CG5715	NP_651242.1	ZnMc_astacin_like	107..291	CDD:239807	74/184 (40%)
mep1ba	NP_001070089.2	ZnMc_meprin	29..258	CDD:239809	88/216 (41%)
		Astacin	72..260	CDD:279708	79/192 (41%)
		MAM	268..432	CDD:279023
		MAM	268..430	CDD:99706
		MATH_Meprin_Beta	430..599	CDD:239751
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25214
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2664
SonicParanoid	1	1.000	-	-		X245
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.940