DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uck and URK1

DIOPT Version :9

Sequence 1:	NP_001138105.1	Gene:	Uck / 42894	FlyBaseID:	FBgn0263398	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_014409.1	Gene:	URK1 / 855746	SGDID:	S000005295	Length:	501	Species:	Saccharomyces cerevisiae

Alignment Length:	217	Identity:	87/217 - (40%)
Similarity:	129/217 - (59%)	Gaps:	9/217 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLFNF 90
            :|::||:.|.:.|||::|..||:..:...       ..|.||.|:||..|.|.::|:|.|..::|
Yeast    55 TPYIIGIGGASGSGKTSVAAKIVSSINVP-------WTVLISLDNFYNPLGPEDRARAFKNEYDF 112

  Fly    91 DHPDAFNEELMYSTLQNILKGHKVEIPSYDY-RTNSLDFENVLVIYPADVVLFEGILVFYFPKIR 154
            |.|:|.|.:|.|..:.|:.:|.:..||.|.: ..|.:..:|: |||.|.||:.|||...|..::.
Yeast   113 DEPNAINLDLAYKCILNLKEGKRTNIPVYSFVHHNRVPDKNI-VIYGASVVVIEGIYALYDRRLL 176

  Fly   155 ELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIPRG 219
            :|..:|::||.|.|..||||:.|||..||||||..:.|:..||||...:|..||.|.||.|||..
Yeast   177 DLMDLKIYVDADLDVCLARRLSRDIVSRGRDLDGCIQQWEKFVKPNAVKFVKPTMKNADAIIPSM 241

  Fly   220 ADNTVAIDLIVQHIRDFLNNRS 241
            :||..|::||:.||:..|..:|
Yeast   242 SDNATAVNLIINHIKSKLELKS 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	84/206 (41%)
URK1	NP_014409.1	udk	69..260	CDD:272977	79/198 (40%)
URK1	NP_014409.1	Upp	280..501	CDD:223113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343298
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1209
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.620