Protein Alignment Uck and Jup

DIOPT Version :10

• Sequence 1: NP_001138105.1
• Gene: Uck / 42894
• FlyBaseID: FBgn0263398
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: NP_112309.2
• Gene: Jup / 81679
• RGDID: 620412
• Length: 745
• Species: Rattus norvegicus
• Alignment Length: 106
• Identity: 21/106 - (19%)
• Similarity: 44/106 - (41%)
• Gaps: 17/106 - (16%)

  Fly    40 KSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLFNFDHPDAFNE------ 98
            ::.|..::::.|.:|..| .||.|.:.:|..:...:...|..:...|..:....|..|.
  Rat   520 EAAVIPRLVQLLVKAHQD-AQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRL 583

  Fly    99 -------ELMYSTLQNILK---GHKVEIPSYDYRTNSLDFE 129
                   :|:||:::||.:   |...|:.......:::|.|
  Rat   584 NTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAE 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	21/106 (20%)
Jup	NP_112309.2	CTNNAbd_CTNNB1-like	73..142	CDD:459249
		Adaptin_N	<120..>289	CDD:396262
		Interaction with DSC1 and DSG1. /evidence=ECO:0000250	132..297
		armadillo repeat	144..169	CDD:293788
		armadillo repeat	186..212	CDD:293788
		armadillo repeat	221..253	CDD:293788
		Arm	221..253	CDD:425727
		armadillo repeat	261..297	CDD:293788
		ARM 5	298..341
		armadillo repeat	305..338	CDD:293788
		PLN03200	<328..>658	CDD:215629	21/106 (20%)
		ARM	341..381	CDD:214547
		ARM 6	342..381
		armadillo repeat	345..380	CDD:293788
		ARM 7	383..420
		armadillo repeat	393..418	CDD:293788
		ARM 8	423..464
		armadillo repeat	426..464	CDD:293788
		ARM 9	470..510
		armadillo repeat	470..508	CDD:293788
		ARM 10	512..551		8/31 (26%)
		armadillo repeat	515..572	CDD:293788	10/52 (19%)
		Interaction with DSC1. /evidence=ECO:0000250	574..661		10/51 (20%)
		armadillo repeat	577..611	CDD:293788	6/33 (18%)
		armadillo repeat	618..652	CDD:293788	2/7 (29%)