Protein Alignment Uck and UCKL1

DIOPT Version :9

• Sequence 1: NP_001138105.1
• Gene: Uck / 42894
• FlyBaseID: FBgn0263398
• Length: 305
• Species: Drosophila melanogaster
• Sequence 2: XP_024307683.1
• Gene: UCKL1 / 54963
• HGNCID: 15938
• Length: 612
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 124/372 - (33%)
• Similarity: 182/372 - (48%)
• Gaps: 107/372 - (28%)

  Fly    25 KSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYR--------ELTPAEKA 81
            |..|.||:.||:||||:||.:.|:|.|...       .||.:|.||||:        .||..::.
Human    96 KEAFAIGLGGGSASGKTTVARMIIEALDVP-------WVVLLSMDSFYKLLHSLPHQVLTEQQQE 153

  Fly    82 KAQKGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNS--LDFENVLVIYPADVVLFEG 144
            :|....|||||||||:.:|:.|||:.:.:|..|::|.||:.|:|  .|::   .:|.|:|::|||
Human   154 QAAHNNFNFDHPDAFDFDLIISTLKKLKQGKSVKVPIYDFTTHSRKKDWK---TLYGANVIIFEG 215

  Fly   145 ILVFYFPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTK 209
            |:.|....:.||..||:|||||||.||.||:.|||:|||||::.|:.||..||||:|:::..||.
Human   216 IMAFADKTLLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPSFDQYIQPTM 280

  Fly   210 KFADVIIPRGADNTVAIDLIVQHIRDFL----------------------------NNRSRHGST 246
            :.||:::|||:.|||||||||||:...|                            .:...|...
Human   281 RLADIVVPRGSGNTVAIDLIVQHVHSQLEEGCAGLGTPVPPAAPDAERPEEHAAGTGHAHHHQGQ 345

  Fly   247 GNMALYMNLDLNAT-----------------------GAG-----FAGPDGSNLGT--------- 274
            |:.:..::|.|..|                       |||     ..|..|:.|||
Human   346 GDQSRRVHLLLQETDAAAHRARALLPALSGLRRTDPAGAGLCGQVLCGEAGTCLGTPGRGTGCWG 410

  Fly   275 --------------YNAIRRFST-------ICKELNMQGNYFFETNK 300
                          .:.:|...|       :||::.: |....:||:
Human   411 GMWALSLPSPQITGVSILRAGETMEPALRAVCKDVRI-GTILIQTNQ 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	101/215 (47%)
UCKL1	XP_024307683.1	UMPK	101..307	CDD:238981	101/215 (47%)
		UPRTase	<417..596	CDD:317125	7/41 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.750