DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uck and Uckl1

DIOPT Version :9

Sequence 1:	NP_001138105.1	Gene:	Uck / 42894	FlyBaseID:	FBgn0263398	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	XP_038961641.1	Gene:	Uckl1 / 499956	RGDID:	1565465	Length:	549	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	107/218 - (49%)
Similarity:	149/218 - (68%)	Gaps:	12/218 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLFN 89
            |..|.||:.||:||||:||.:.|:|.|...       .||.:|.||||:.||..::.:|....||
  Rat    96 KEAFAIGLGGGSASGKTTVARMIIEALDVP-------WVVLLSMDSFYKVLTQQQQEQAACNNFN 153

  Fly    90 FDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNS--LDFENVLVIYPADVVLFEGILVFYFPK 152
            |||||||:.:|:.|||:.:.:|..|:||.||:.|:|  .|::   .:|.|:|::||||:.|....
  Rat   154 FDHPDAFDFDLIISTLKKLKQGRSVQIPIYDFTTHSRKKDWK---TLYGANVIIFEGIMAFADKT 215

  Fly   153 IRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIP 217
            :.||..||:|||||||.||.||:.|||:|||||::.|:.||..||||||:::..||.:.||:::|
  Rat   216 LLELLDMKIFVDTDSDIRLVRRLRRDISERGRDIEGVIKQYNKFVKPAFDQYIQPTMRLADIVVP 280

  Fly   218 RGADNTVAIDLIVQHIRDFLNNR 240
            ||:.|||||||||||:...|..|
  Rat   281 RGSGNTVAIDLIVQHVHSQLEER 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	103/207 (50%)
Uckl1	XP_038961641.1	UMPK	101..299	CDD:238981	103/207 (50%)
Uckl1	XP_038961641.1	UPRTase	330..533	CDD:405383
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720