DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uck and uck1

DIOPT Version :9

Sequence 1:	NP_001138105.1	Gene:	Uck / 42894	FlyBaseID:	FBgn0263398	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001004666.1	Gene:	uck1 / 447928	ZFINID:	ZDB-GENE-040912-113	Length:	277	Species:	Danio rerio

Alignment Length:	244	Identity:	155/244 - (63%)
Similarity:	185/244 - (75%)	Gaps:	15/244 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 NGDGAAANDE--VKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELT 76
            |..|...::|  ...||||||:|||||||||||.||||.|||.::||.||:|..:|||||||.||
Zfish     2 NSSGLLCDNERPRHRPFLIGVSGGTASGKSTVCAKIMELLGQNKVDHHQRKVTIVSQDSFYRVLT 66

  Fly    77 PAEKAKAQKGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVL 141
            |.:||||.||.:||||||||:.|.|..||::|::|..||:|:||:.|:|...|.:.| |||||||
Zfish    67 PEQKAKALKGQYNFDHPDAFDTEFMCQTLKDIVEGKVVEVPTYDFVTHSRLPEKICV-YPADVVL 130

  Fly   142 FEGILVFYFPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCS 206
            ||||||||..::|::||||.|||||||.||:|||.||:| |||||:.:||||.|||||||||||.
Zfish   131 FEGILVFYTQEVRDMFHMKQFVDTDSDVRLSRRVLRDMN-RGRDLEQILTQYTTFVKPAFEEFCL 194

  Fly   207 PTKKFADVIIPRGADNTVAIDLIVQHIRDFLN-----------NRSRHG 244
            ||||:||||||||.||.|||:||||||:|.||           |...||
Zfish   195 PTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWQRGSVNGHNHG 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	144/205 (70%)
uck1	NP_001004666.1	Udk	15..226	CDD:223645	147/212 (69%)
		UMPK	19..224	CDD:238981	144/206 (70%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	241..277		2/3 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579262
Domainoid	1	1.000	278	1.000	Domainoid score	I1680
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2658
OMA	1	1.010	-	-		QHG61683
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	1	1.000	-	-		FOG0002695
OrthoInspector	1	1.000	-	-		otm26097
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	1	1.100	-	-	LDO	PTHR10285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	1	1.000	-	-		X2455
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800