DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uck and l(2)k01209

DIOPT Version :9

Sequence 1:	NP_001138105.1	Gene:	Uck / 42894	FlyBaseID:	FBgn0263398	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_725672.2	Gene:	l(2)k01209 / 36953	FlyBaseID:	FBgn0022029	Length:	626	Species:	Drosophila melanogaster

Alignment Length:	221	Identity:	102/221 - (46%)
Similarity:	144/221 - (65%)	Gaps:	9/221 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ANDEVKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQ 84
            |..:|: ||:||:.||:||||:||.:||:|.|...       .|..:|.|.||:.|...:..:|.
  Fly   180 AGQQVE-PFVIGICGGSASGKTTVAEKIIESLDVP-------WVTLLSMDCFYKILNEKQHEQAL 236

  Fly    85 KGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGILVFY 149
            ...:||||||||:.||:...|..:.:|.|||:|.|::.|:..: .....:|.|:|::|||||.|:
  Fly   237 INEYNFDHPDAFDIELLLDVLTKLKEGRKVEVPVYNFVTHGRE-SQTKTMYGANVIIFEGILTFH 300

  Fly   150 FPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADV 214
            .|::.:|..||:|||||.|.|||||:.|||::|||||..||.||:..|||::..:.:||...||:
  Fly   301 SPEVLKLLDMKIFVDTDPDIRLARRLRRDISQRGRDLKGVLKQYLNMVKPSYCNYIAPTMAHADI 365

  Fly   215 IIPRGADNTVAIDLIVQHIRDFLNNR 240
            |:|||.||.|||.|||||:...|..|
  Fly   366 IVPRGGDNKVAIHLIVQHVHTQLQLR 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	96/205 (47%)
l(2)k01209	NP_725672.2	Udk	186..397	CDD:223645	100/214 (47%)
		UMPK	188..387	CDD:238981	96/206 (47%)
		UPRTase	417..620	CDD:291353
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446865
Domainoid	1	1.000	201	1.000	Domainoid score	I867
eggNOG	1	0.900	-	-		E1_COG0572
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm51389
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	1	1.100	-	-	P	PTHR10285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.780