DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uck and uck2b

DIOPT Version :9

Sequence 1:	NP_001138105.1	Gene:	Uck / 42894	FlyBaseID:	FBgn0263398	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_956058.1	Gene:	uck2b / 327057	ZFINID:	ZDB-GENE-030131-5265	Length:	261	Species:	Danio rerio

Alignment Length:	239	Identity:	157/239 - (65%)
Similarity:	189/239 - (79%)	Gaps:	10/239 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DGAAANDEVKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEK 80
            |.|.....|:.||||||:||||||||:||:||||.|||.::|..|||||.:|||||||||||.:|
Zfish    11 DRAENGHAVRQPFLIGVSGGTASGKSSVCEKIMELLGQNKIDRHQRQVVILSQDSFYRELTPEQK 75

  Fly    81 AKAQKGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGI 145
            |||.||.|||||||||:.||:..||::|::|..|.||.||:.|:|.. :..|.:|||||||||||
Zfish    76 AKAVKGQFNFDHPDAFDSELIMKTLRDIIQGKTVHIPVYDFVTHSRK-DEFLTLYPADVVLFEGI 139

  Fly   146 LVFYFPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKK 210
            |:||..:||:||.||||||||.||||:|||.|||:||||:|:.||.||:|||||||||||.||||
Zfish   140 LMFYSQEIRDLFKMKLFVDTDPDTRLSRRVLRDISERGRELEQVLNQYITFVKPAFEEFCLPTKK 204

  Fly   211 FADVIIPRGADNTVAIDLIVQHIRDFLNN---------RSRHGS 245
            :|||||||||||.|||:||||||:|.||.         ::.||:
Zfish   205 YADVIIPRGADNLVAINLIVQHIQDILNGGFTKRQNGFQNGHGT 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	147/205 (72%)
uck2b	NP_956058.1	Udk	17..232	CDD:223645	151/215 (70%)
		UMPK	24..230	CDD:238981	147/206 (71%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	238..261		2/11 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579261
Domainoid	1	1.000	278	1.000	Domainoid score	I1680
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2658
OMA	1	1.010	-	-		QHG61683
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	1	1.000	-	-		FOG0002695
OrthoInspector	1	1.000	-	-		otm26097
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	1	1.100	-	-	O	PTHR10285
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2455
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770