DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uck and Uck1

DIOPT Version :9

Sequence 1:	NP_001138105.1	Gene:	Uck / 42894	FlyBaseID:	FBgn0263398	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001365720.1	Gene:	Uck1 / 22245	MGIID:	98904	Length:	301	Species:	Mus musculus

Alignment Length:	243	Identity:	148/243 - (60%)
Similarity:	181/243 - (74%)	Gaps:	24/243 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLFNFD 91
            ||||||:|||||||||||:||||.|||.|:|..||::|.:|||.||:.||..:||||.||.:|||
Mouse    29 PFLIGVSGGTASGKSTVCEKIMELLGQNEVDRRQRKLVILSQDCFYKVLTAEQKAKALKGQYNFD 93

  Fly    92 HPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGILVFYFPKIREL 156
            |||||:.:||:.||:||::|..||:|:||:.|:| ......|:|||||||||||||||..:||::
Mouse    94 HPDAFDNDLMHKTLKNIVEGKTVEVPTYDFVTHS-RLPETTVVYPADVVLFEGILVFYTQEIRDM 157

  Fly   157 FHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIPRGAD 221
            ||::||||||||.||:|||.||: :|||||:.:||||..||||||||||.||||:||||||||.|
Mouse   158 FHLRLFVDTDSDVRLSRRVLRDV-QRGRDLEQILTQYTAFVKPAFEEFCLPTKKYADVIIPRGVD 221

  Fly   222 N------------------TVAIDLIVQHIRDFLN----NRSRHGSTG 247
            |                  .|||:||||||:|.||    .|.|.|..|
Mouse   222 NMADQARTLDCACPVGCLLPVAINLIVQHIQDILNGDLCKRHRGGPNG 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	139/223 (62%)
Uck1	NP_001365720.1	UMPK	31..254	CDD:238981	139/224 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835888
Domainoid	1	1.000	271	1.000	Domainoid score	I1811
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	292	1.000	Inparanoid score	I2760
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61683
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	1	1.000	-	-		FOG0002695
OrthoInspector	1	1.000	-	-		otm43100
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	1	1.100	-	-	LDO	PTHR10285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	1	1.000	-	-		X2455
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800