DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uck and F19B6.1

DIOPT Version :9

Sequence 1:	NP_001138105.1	Gene:	Uck / 42894	FlyBaseID:	FBgn0263398	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001368094.1	Gene:	F19B6.1 / 178181	WormBaseID:	WBGene00008948	Length:	569	Species:	Caenorhabditis elegans

Alignment Length:	229	Identity:	110/229 - (48%)
Similarity:	156/229 - (68%)	Gaps:	17/229 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 VKSPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGLF 88
            :|.||:|||.||:||||:||.:||:|:||..       .|..:|.||||:.|||.|...|.:..:
Worm   115 LKHPFVIGVCGGSASGKTTVAEKIVERLGIP-------WVTILSMDSFYKVLTPEEIKAAHESRY 172

  Fly    89 NFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGILVFYFPKI 153
            |||.|:||:.:|:|..|:.:.:|..|::|.||:.|:|.| .|..::|.|||::|||||.|:..:|
Worm   173 NFDGPNAFDFDLLYEVLKRLREGKSVDVPVYDFNTHSRD-PNSKMMYGADVLIFEGILAFHDERI 236

  Fly   154 RELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIPR 218
            :.|..||:|||||.|.|||||:.||:.:||||:|.::.||.|||||||:::.:|....||:|:||
Worm   237 KNLMDMKVFVDTDGDLRLARRIVRDVTDRGRDIDGIMEQYFTFVKPAFDKYIAPCMDSADLIVPR 301

  Fly   219 GADNTVAIDLIVQHIRDFL---------NNRSRH 243
            |.:|.||||:|||::...|         |||.||
Worm   302 GGENDVAIDMIVQNVMAQLVERGYDRNQNNRDRH 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	101/205 (49%)
F19B6.1	NP_001368094.1	UMPK	120..319	CDD:238981	101/206 (49%)
F19B6.1	NP_001368094.1	UPRTase	355..557	CDD:405383
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850