DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uck and B0001.4

DIOPT Version :9

Sequence 1:	NP_001138105.1	Gene:	Uck / 42894	FlyBaseID:	FBgn0263398	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_502304.2	Gene:	B0001.4 / 178160	WormBaseID:	WBGene00007089	Length:	248	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	104/213 - (48%)
Similarity:	147/213 - (69%)	Gaps:	3/213 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 VKSPFLIGVAGGTASGKSTVCKKIMEQL-GQAEMDHTQRQVVSISQDSFYRELTPAEKAKAQKGL 87
            :|.|.||||||||:.||||:.::|:|.| ..|:....|..:|.:|..||||||:..||..|::|.
Worm     5 LKLPLLIGVAGGTSCGKSTIVERIIENLNANAKQSGRQIDIVHLSLHSFYRELSAEEKILAREGK 69

  Fly    88 FNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEGILVFYFPK 152
            |||||||..|.:|:..||||::.|..||||.||..|:|::  ..:.:.||.|::.||||:.|..:
Worm    70 FNFDHPDQINFDLLAETLQNMIDGKTVEIPKYDMITSSMN--GTVTVEPAKVIIIEGILLLYDER 132

  Fly   153 IRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTKKFADVIIP 217
            :|:|...||||:.::::||..|:...|.:..|...:::.||..||||||||||.||||:||||||
Worm   133 VRKLLSTKLFVEKNAESRLRNRLATYIRDYHRAPLSIIRQYTEFVKPAFEEFCRPTKKYADVIIP 197

  Fly   218 RGADNTVAIDLIVQHIRD 235
            |||||.||.|||.:::::
Worm   198 RGADNHVATDLIAKNLQE 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	102/206 (50%)
B0001.4	NP_502304.2	Udk	1..223	CDD:223645	104/213 (49%)
B0001.4	NP_502304.2	UMPK	10..216	CDD:238981	102/208 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158692
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	202	1.000	Inparanoid score	I2459
Isobase	1	0.950	-	0	Normalized mean entropy	S1209
OMA	1	1.010	-	-		QHG61683
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	1	1.000	-	-		FOG0002695
OrthoInspector	1	1.000	-	-		oto20415
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	1	1.100	-	-	LDO	PTHR10285
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.720