DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uck and uck2a

DIOPT Version :9

Sequence 1:	NP_001138105.1	Gene:	Uck / 42894	FlyBaseID:	FBgn0263398	Length:	305	Species:	Drosophila melanogaster
Sequence 2:	NP_001164538.1	Gene:	uck2a / 100005763	ZFINID:	ZDB-GENE-030131-7158	Length:	261	Species:	Danio rerio

Alignment Length:	246	Identity:	162/246 - (65%)
Similarity:	188/246 - (76%)	Gaps:	17/246 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DGAAANDEVK-SPFLIGVAGGTASGKSTVCKKIMEQLGQAEMDHTQRQVVSISQDSFYRELTPAE 79
            |..|.|:.|. .|||||||||||||||:||.||||.|||.::||.||||..:|||||||.|||.:
Zfish    10 DNHAENEHVDWQPFLIGVAGGTASGKSSVCGKIMELLGQNKIDHHQRQVAILSQDSFYRVLTPEQ 74

  Fly    80 KAKAQKGLFNFDHPDAFNEELMYSTLQNILKGHKVEIPSYDYRTNSLDFENVLVIYPADVVLFEG 144
            ||||.||.|||||||||:.||:..||..|::|..|:||.||:.|:|.. |..:.:||||||||||
Zfish    75 KAKALKGQFNFDHPDAFDNELIVKTLCEIMEGRTVQIPVYDFVTHSRK-EETVTVYPADVVLFEG 138

  Fly   145 ILVFYFPKIRELFHMKLFVDTDSDTRLARRVPRDINERGRDLDAVLTQYMTFVKPAFEEFCSPTK 209
            ||:||..:||:||.||||||||:||||:|||.|||:||||||:.||.||:|||||||||||.|||
Zfish   139 ILMFYSQEIRDLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQVLNQYITFVKPAFEEFCLPTK 203

  Fly   210 KFADVIIPRGADNTVAIDLIVQHIRDFLNN---------------RSRHGS 245
            |:|||||||||||.|||:||||||:||||.               |.||.|
Zfish   204 KYADVIIPRGADNLVAINLIVQHIQDFLNGGLTKRLNGCLNGHTPRKRHPS 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uck	NP_001138105.1	UMPK	29..235	CDD:238981	148/205 (72%)
uck2a	NP_001164538.1	Udk	21..232	CDD:223645	152/211 (72%)
uck2a	NP_001164538.1	UMPK	24..229	CDD:238981	148/205 (72%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579260
Domainoid	1	1.000	278	1.000	Domainoid score	I1680
eggNOG	1	0.900	-	-		E1_COG0572
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H40850
Inparanoid	1	1.050	301	1.000	Inparanoid score	I2658
OMA	1	1.010	-	-		QHG61683
OrthoDB	1	1.010	-	-		D509086at33208
OrthoFinder	1	1.000	-	-		FOG0002695
OrthoInspector	1	1.000	-	-		otm26097
orthoMCL	1	0.900	-	-		OOG6_100147
Panther	1	1.100	-	-	O	PTHR10285
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1606
SonicParanoid	1	1.000	-	-		X2455
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800