Protein Alignment CG6356 and SLC22A13

DIOPT Version :9

• Sequence 1: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 563
• Identity: 140/563 - (24%)
• Similarity: 258/563 - (45%)
• Gaps: 66/563 - (11%)

  Fly    28 LEVVGSGGAF-VWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWT-HAQKREIV 90
            |..:|..|.| :..:..|||. |.|:.|:..::..: .|.:...|.:..:::..:. .|.::.::
Human     8 LAEIGDFGRFQIQLLILLCVL-NFLSPFYFFAHVFM-VLDEPHHCAVAWVKNHTFNLSAAEQLVL 70

  Fly    91 AKGLDSGGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEF----------AH 145
            :..||:.|              ..|..|.:.      .|||..|.:....|.|          .:
Human    71 SVPLDTAG--------------HPEPCLMFR------PPPANASLQDILSHRFNETQPCDMGWEY 115

  Fly   146 PETTFVA---DWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSF 207
            ||....:   :::|.|||...:.:.|.....|...|:..||.|.|:.|||::.......|.:...
Human   116 PENRLPSLKNEFNLVCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGRKATILAQLLLFTLIGL 180

  Fly   208 FCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGY 272
            ...|.|.:.|::|.|||:..|.:||.:...|::.|.:....|:...:....::.:|.::||.:.|
Human   181 ATAFVPSFELYMALRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAVVLAQCNFSLGQMVLAGLAY 245

  Fly   273 VIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQV 337
            ..:.||.||:..|.|.|||....:.:.||.|||:|..|.|...::         ||.|.:.
Human   246 GFRNWRLLQITGTAPGLLLFFYFWALPESARWLLTRGRMDEAIQL---------IQKAASV---- 297

  Fly   338 ASDKKSLEPEEGFSFGQKL--KNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAAN 400
              :::.|.||   ...|.:  |.||..:.::|:.:.::|::....:.::.|.||.||..:|...:
Human   298 --NRRKLSPE---LMNQLVPEKTGPSGNALDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGD 357

  Fly   401 LSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFA 465
            ..:..||..:..|.|::|:....:.|::..||:.:.:...:..|:..::::.:||.....:...|
Human   358 FGLDVYLTQLIFGAVEVPARCSSIFMMQRFGRKWSQLGTLVLGGLMCIIIIFIPADLPVVVTMLA 422

  Fly   466 MLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICG 530
            ::|:...:|.:::..:|:|||:||.:|.:.:|....|:.:|.|..|.|: :||.....:|..|.|
Human   423 VVGKMATAAAFTISYVYSAELFPTILRQTGMGLVGIFSRIGGILTPLVI-LLGEYHAALPMLIYG 486

  Fly   531 CCVLVAGLLTLTLPETGTGKLSDKVES--------SASSTPTE 565
            ...:|||||...||||....|.|.::.        |..|.|:|
Human   487 SLPIVAGLLCTLLPETHGQGLKDTLQDLELGPHPRSPKSVPSE 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	100/378 (26%)
SLC22A13	NP_004247.2	2A0119	12..510	CDD:273328	134/538 (25%)
		MFS	139..500	CDD:119392	100/379 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		4/19 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153605
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.910