DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and HXT5

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_011964.1	Gene:	HXT5 / 856496	SGDID:	S000001138	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	553	Identity:	115/553 - (20%)
Similarity:	200/553 - (36%)	Gaps:	113/553 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 NILNGFHVSSYTLLGHLPDDQWCGIPELQ---DTNWTHAQKREI----VAKGLDSGGCTVWDWNY 106
            |:.....||||......|.|:   :.|||   |.......|.::    |...:.:.|..|:.|:.
Yeast    43 NLAQAKPVSSYISHEGPPKDE---LEELQKEVDKQLEKKSKSDLLFVSVCCLMVAFGGFVFGWDT 104

  Fly   107 GHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSI 171
            |.::     ..:..|..:.:..     |.|..|        ||:::|         .||...|||
Yeast   105 GTIS-----GFVRQTDFIRRFG-----STRANG--------TTYLSD---------VRTGLMVSI 142

  Fly   172 -SLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSF--FCTFSPWYSLFLAGRFALGAASSGLF 233
             ::|...|......|.|.:|||.........:.:|..  ..:...||..|: ||...|....|:.
Yeast   143 FNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFI-GRIISGLGVGGIT 206

  Fly   234 YPAFTMIVENICLKH-RSWMSIAFSASYPVGMIILAIVGYVIQ----------PWRHLQLALTIP 287
            ..| .|::..:..|. |..:...:......|:.:    ||...          .|| :.|.|...
Yeast   207 VLA-PMLISEVSPKQLRGTLVSCYQLMITFGIFL----GYCTNFGTKNYSNSVQWR-VPLGLCFA 265

  Fly   288 -SLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVASDKKSLEPEE--- 348
             |:.:|:....:.||||:|:...:.:...:.|.|.....:..|.|..  ::.:.:.|:|.|.
Yeast   266 WSIFMIVGMTFVPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTL--EMENYQSSIEAERLAG 328

  Fly   349 GFSFGQKLKNGPLKSIIELYANSKVRRMIFA-------SYFMFCVTSLSYYVTALNAANLSVSRY 406
            ..|:|:.:...|     :::..:.:..||.:       :||.:      |..|...|..|..|..
Yeast   329 SASWGELVTGKP-----QMFRRTLMGMMIQSLQQLTGDNYFFY------YGTTIFQAVGLEDSFE 382

  Fly   407 LYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPA---------------- 455
            ..|: .|:|:..|....:..:...|||    ...||..|.::....|.|
Yeast   383 TAIV-LGVVNFVSTFFSLYTVDRFGRR----NCLLWGCVGMICCYVVYASVGVTRLWPNGQDQPS 442

  Fly   456 --GSTTWIVAFAMLGRFGISATYS-VVTLYTAELYPTQIRNSALGTCST----FAHVGSISAPYV 513
              |:...::.||....|..:.|:: |..:..:|.||.::|..|:...|.    :..:.|...|::
Yeast   443 SKGAGNCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFI 507

  Fly   514 VDVLGALGWYIPTTICGCCVLVAGLLTLTLPET 546
            .   .|:.:|......||.|.....:...:|||
Yeast   508 T---SAINFYYGYVFMGCMVFAYFYVFFFVPET 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	86/424 (20%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	102/504 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000