Protein Alignment CG6356 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001028339.1
• Gene: Slc22a23 / 73102
• MGIID: 1920352
• Length: 689
• Species: Mus musculus
• Alignment Length: 608
• Identity: 141/608 - (23%)
• Similarity: 235/608 - (38%)
• Gaps: 118/608 - (19%)

  Fly    32 GSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIVAKGLDS 96
            |.||.:...:..|...|.:..||...|.:.|...| |.||                ....||.:.
Mouse    90 GLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQP-DFWC----------------RGAGKGTEL 137

  Fly    97 GGCTV---W----DWNYGHLAKMSYEAALNYTGHLTQI-------SPPAEVSCRVKGQ------- 140
            .|.||   |    :|........| .|:...|.:.:..       |||.      ||.
Mouse   138 AGATVTGRWGDMGNWTSPSATPFS-TASWGTTSNRSNSSDTPPLPSPPG------KGNNDSNCDC 195

  Fly   141 HEFAHPETT-----FVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAA 200
            |.:.:...|     .|:.|||.||.:.:...|:.|:.:|...|....|.:||..||:........
Mouse   196 HAWDYGIRTGLIQNVVSKWDLVCDNTWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSTI 260

  Fly   201 FFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMI 265
            |.::.......|...::|...||..|...:|:....:.:.:| :|...:.:: |...||:
Mouse   261 FILIFGLTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIE-LCPPGKRFI-ITMVASF----- 318

  Fly   266 ILAIVGYVIQP--------WRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQP 322
             :|:.|..:.|        |:.||..:..|.||::|...:..||.|||:..|:::...|::.
Mouse   319 -VAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLIL--- 379

  Fly   323 SHYQIQPAVAAPSQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVT 387
              |..|....:|.   ||.|.:.||    ..::|...|.|..|.....:   |.::.:..:.||.
Mouse   380 --YLTQKNCVSPE---SDIKGVMPE----LEKELSRRPKKVCIVKVVGT---RNLWKNIVVLCVN 432

  Fly   388 SLSYY------VTALNAANLSV----SRYLYIIGTGLVDIPSYLVPVIMLRFTGRR--------L 434
            ||:.|      ..::....:.|    :.|........:.:.|.|...::::|.|||        |
Mouse   433 SLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIALASCLAMCLVVKFLGRRGGLLLFMIL 497

  Fly   435 TTMFLFLWTGV-------------SLLLVLAVPAGSTT---WIVAFAMLGRFGISATYSVVTLYT 483
            |.:...|..|:             .|.|.|||....:.   :.:||:::|.|...|..|:...:.
Mouse   498 TALASLLQLGLLNLIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFC 562

  Fly   484 AELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPETGT 548
            ||:.||.||...||.....|..|.::|| ::::....|:::...|..||.|:..:..|.|||:..
Mouse   563 AEITPTVIRCGGLGLVLASAGFGMLTAP-IIELHNQKGYFLHHIIFACCTLICIICILLLPESRN 626

  Fly   549 GKLSDKVESSASST--PTEPAEK 569
            ..|.:.:.:....|  |..|.:|
Mouse   627 QNLPENIANGEHYTRQPLLPHKK 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	97/418 (23%)
Slc22a23	NP_001028339.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		2A0119	98..631	CDD:273328	134/580 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		6/31 (19%)
		MFS	230..>359	CDD:119392	30/136 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843349
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030