DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and LOC685081

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	XP_008764922.2	Gene:	LOC685081 / 685081	RGDID:	1583222	Length:	621	Species:	Rattus norvegicus

Alignment Length:	550	Identity:	139/550 - (25%)
Similarity:	244/550 - (44%)	Gaps:	58/550 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWT-HAQKREIVAKGL 94
            ||..|.|...:..|...||.|:.|.|.|...: .|.:...|.:..:::..:. .|.::..|:...
  Rat    11 VGDFGPFQVRVTILMGIPNFLSAFFVFSQVFM-VLDEAHHCSVSWVKNHTFNLSAAEQLAVSIPN 74

  Fly    95 DSGGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEF----------AHPET- 148
            |:.|              ..|:.|.:.      .||...|......|.|          .:||.
  Rat    75 DTAG--------------RPESCLMFR------PPPDSASLEDILSHRFNETQACDSGWDYPENR 119

  Fly   149 --TFVADWDLTCDR-SIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCT 210
              :...::||.|:| :::|||..|.:: |...|:..||.:.|..||::|..|......:......
  Rat   120 PPSLKNEFDLVCERENLKRTSQSVFMA-GLLVGALVFGPVCDWIGRRASILLQVLLSGITGVATA 183

  Fly   211 FSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGYVIQ 275
            |.|.:.|::...|....|.:|.......::.|.:....|:...:...:::.:|::.||.:.|.::
  Rat   184 FVPSFELYMVLCFFSAIAVAGYMMSTMILVSEWVGPSWRTRAMVLAQSNFALGLMALAGLAYGVR 248

  Fly   276 PWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQ-VAS 339
            .||.||:..|.|..||:...:::.||||||::..|.:...::         :|.|.....: :||
  Rat   249 NWRLLQIIGTTPIFLLVFYFWVLPESPRWLLSQGRTEEAKQL---------VQKAALVNGRPLAS 304

  Fly   340 D-KKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSV 403
            : ...|.||         |.||..:.::|:.:.::|::......::.|.||.||.......:..:
  Rat   305 ELLNQLVPE---------KTGPSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGL 360

  Fly   404 SRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLG 468
            ..||..:..|:|::|:.|..:.|:...||:.:.:......||..::::.:|....|...|.|::|
  Rat   361 DIYLTQVIFGVVEVPARLSSIPMMEKLGRKWSQLCTLTLAGVMCVIIIFIPGDLPTVATALAVVG 425

  Fly   469 RFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCV 533
            :|..||.:::..:|||||.||.||.:.:|..|.|:.||.|..|.|: :|......||..|.|...
  Rat   426 KFASSAAFTISYVYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVM-LLEQYHKAIPMLIFGSLP 489

  Fly   534 LVAGLLTLTLPETGTGKLSDKVESSASSTP 563
            :.||||...||||....|.|.::......|
  Rat   490 IGAGLLCALLPETRGQTLKDTLQDLEQGGP 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	99/378 (26%)
LOC685081	XP_008764922.2	2A0119	12..510	CDD:273328	136/538 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347194
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.950