Protein Alignment CG6356 and Slc22a17

DIOPT Version :10

• Sequence 1: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_001347335.2
• Gene: Slc22a17 / 59049
• MGIID: 1926225
• Length: 627
• Species: Mus musculus
• Alignment Length: 573
• Identity: 129/573 - (22%)
• Similarity: 206/573 - (35%)
• Gaps: 112/573 - (19%)

  Fly    22 DLLTKQLEVVGSGGAFVWAIFFLCVTPNILNGFHVSS---YTL-------LGHLPDDQWCGIPEL 76
            :.|..|:..:|.|......   ||..|.:.....::|   :||       .|.||.:.
Mouse    77 EALLAQVGALGGGQQLQLG---LCCLPVLFVALGMASDPIFTLAPPLHCHYGALPPNA------- 131

  Fly    77 QDTNWTHAQKREIVAKGLDSGGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQH 141
              :.|.....    :.|:...|..:              ||...:|.:|...|    ||......
Mouse   132 --SGWEQPPN----SSGVSVAGAAL--------------AASAASGVVTSTDP----SCSGFAPP 172

  Fly   142 EFAH----------P--ETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSS 194
            :|.|          |  .|..:..|||.||...|....|:...||...|....|..||:|||:..
Mouse   173 DFNHCLKDWDYNGLPVLTTNAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGRRGI 237

  Fly   195 FTL-----------GAAFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKH 248
            ..|           |||   .||        .:..:|.||.||...:|:....:.|.:|......
Mouse   238 VLLTLGLVGPCGVGGAA---AGS--------STGIMALRFLLGFLLAGVDLGVYLMRLELCDPTQ 291

  Fly   249 RSWMSIAFSASYPVGMIILAIVGYVIQPWRHLQLALTIPSLLLILNCY--LMSESPRWLITNQRY 311
            |..:::|.......|..:...:..|.:.||.||..:|.|.:|.:...:  |..||.||||..::.
Mouse   292 RLRVALAGELVGVGGHFLFLGLALVSKDWRFLQRMITAPCILFLFYGWPGLFLESARWLIVKRQI 356

  Fly   312 DRVYKIL----FRQPSHYQIQPAVAAPS-QVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANS 371
            :....:|    .|...|.|:....|..: |...:...|.....|||...|.          |.|.
Mouse   357 EEAQSVLRILAERNRPHGQMLGEEAQEALQELENTCPLPATSTFSFASLLN----------YRNI 411

  Fly   372 KVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYL-YIIGTGLVDIPSYLVPVIMLRFTGRRLT 435
             .:.::...:..|...::.:....:.........|| .::.:|...:....:.|.:.|| |||..
Mouse   412 -WKNLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRF-GRRGI 474

  Fly   436 TMFLFLWTGVSLLLVLAVPAGSTTW-------IVAFAMLGRFGISATYSVVTLYTAELYPTQIRN 493
            .:.....||::.|::|.:      |       |..|::||.|...|:..:.||..:|:.||.:|.
Mouse   475 LLLSMTLTGIASLVLLGL------WDYLNDAAITTFSVLGLFSSQASAILSTLLASEVIPTTVRG 533

  Fly   494 SALGTCSTFAHVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPET 546
            ..||.......:|.:|.|.....:|. |.::...:...|.|:..|..:.||||
Mouse   534 RGLGLIMALGALGGLSCPAQRLHMGH-GAFLQHVVLAACALLCILSIMLLPET 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS_SLC22	140..544	CDD:340875	102/441 (23%)
Slc22a17	NP_001347335.2	MFS_SLC22A17	170..583	CDD:341003	102/442 (23%)