DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6356 and si:dkey-119m7.4

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001038399.1	Gene:	si:dkey-119m7.4 / 560629	ZFINID:	ZDB-GENE-040724-70	Length:	413	Species:	Danio rerio

Alignment Length:	447	Identity:	105/447 - (23%)
Similarity:	187/447 - (41%)	Gaps:	55/447 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KQLEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQKREIV 90
            |.|:.:|..|.|...::.....|.|...||:......|.:|       |.|..::|...
Zfish     5 KVLDRIGGFGRFQKTLYVWICLPQIFLAFHMLVSVFTGAVP-------PHLCRSSWPVG------ 56

  Fly    91 AKGLDSGG--------------CTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQH 141
                ||.|              ||           .|.:.:|....|...|:..:..:....|..
Zfish    57 ----DSAGPRLNLSFSSAPGESCT-----------PSQDGSLPQRNHSLPITEHSSTAKGCTGGW 106

  Fly   142 EFAHPE--TTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIV 204
            ||:...  :|...:|||.|:.:............|...|:..||.||||:||:....:|.|...:
Zfish   107 EFSKEVFLSTIATEWDLVCENATMNNIGSSIYMFGLLVGAVLFGALADKYGRRIIILIGLAIQAI 171

  Fly   205 GSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAI 269
            ......|:|.:.:::..||.:|...|.:...||.:..|....|.|....:.....:..|.|:||.
Zfish   172 FGVGAAFAPNFYIYVLLRFVVGTTVSAVIMNAFVLGTEWTGPKKRMLAGVITDYFFGFGYILLAG 236

  Fly   270 VGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAP 334
            |.|:|:.||.||||::.||.|.:...:::.:|.|||:.|.:::.... |.|:.:....:|.....
Zfish   237 VAYLIRDWRKLQLAISAPSFLFLFYVWVLPKSARWLMANNKHEEALD-LIRKAALINGKPLEDDD 300

  Fly   335 SQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAA 399
            .::....||.|         ||:.....::::|....::|:.....::::.|..|.||..:||.:
Zfish   301 MELYQSPKSSE---------KLQEQRKYTVLDLVRTPRMRKQSLILFYLWFVNVLVYYGLSLNIS 356

  Fly   400 NLSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAG 456
            :..::.||..:..|||::|:..:.:..|. ..||::.:......|::.||.:.:|.|
Zfish   357 DFGMNIYLTQMIFGLVEMPARTITLFTLN-RSRRISQLAFLAVGGLACLLTIFIPDG 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	74/290 (26%)
si:dkey-119m7.4	NP_001038399.1	2A0119	11..413	CDD:273328	103/441 (23%)
si:dkey-119m7.4	NP_001038399.1	MFS	112..>273	CDD:119392	47/160 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588764
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.950