DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and slc22a13b

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	XP_017209322.1	Gene:	slc22a13b / 556601	ZFINID:	ZDB-GENE-061013-532	Length:	549	Species:	Danio rerio

Alignment Length:	570	Identity:	157/570 - (27%)
Similarity:	250/570 - (43%)	Gaps:	81/570 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 TKQLEVVGSGGAFVWAIFFLCVTPNILNGFHV--SSYTLLG--HLPDDQWC--GIPELQDTNWTH 83
            |:.|..||..|||...:......|||...||:  ..:|.:.  |..:..|.  ..|.|.:
Zfish     5 TQILSSVGEFGAFQKRLLVAVCLPNIFTAFHMFGQVFTAISFPHYCNSSWILRQAPNLTE----- 64

  Fly    84 AQKREIVAKGLDSGGCTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEV--------------S 134
             :|:..:...|||.|              .||:...:|        |.|:              |
Zfish    65 -EKQLNLTVPLDSKG--------------QYESCKMFT--------PVEMDIEDIEHYGINTTTS 106

  Fly   135 CRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGA 199
            |.....::.....:|.:.::||.|:..:...::|.....|...|:..||.:|||:||:.:..|..
Zfish   107 CIDGWVYKAPKDSSTLITEFDLVCENKVYSEASQSIYMAGLLVGALLFGPMADKYGRRFATLLSL 171

  Fly   200 AFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGM 264
            ....:......|||...:::|.||.:|...||:....|.:..|......|:..:|.....:.:|:
Zfish   172 FLQFLSGVGVAFSPNIYVYIALRFVVGTTISGISINTFVLGTEWCGSAKRALFTILSHCFFAIGL 236

  Fly   265 IILAIVGYVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQP 329
            ::|:.|.|.|:.||.|||.|:.|..|..:..:::.||.|||:|..:.|...:         :|..
Zfish   237 MLLSGVAYGIRNWRVLQLVLSAPVGLFFIYYWILPESARWLLTQGKLDSAKR---------EILK 292

  Fly   330 AVAAPSQVASDK--KSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYY 392
            |.....:..|:.  ..:|.|         ......::|:|:....:|:......:|:.||||.||
Zfish   293 AARINGRKVSENLLDKMEAE---------NTAKSSTMIDLFRVGYLRKRALIMCYMWFVTSLVYY 348

  Fly   393 VTALNAANLSVSRYLYIIGTGLVDIPSYL--VPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPA 455
            ..:||..|..:..||..:..|:.:.|:.|  .|:|. || |||:....:.|..|.:.|::.|:||
Zfish   349 GVSLNVGNFGLDIYLTQLIFGMAEFPARLSCFPLIQ-RF-GRRICQSVVLLLGGTACLIIPAIPA 411

  Fly   456 GSTTWIVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGAL 520
            .....:...|::|:|.::|::|:|.:||||||||.:|.:.:|..|..|.|..|.||    ::|.|
Zfish   412 KYPIVVTVIAVIGKFSLAASFSIVYVYTAELYPTVVRQNGVGLNSMCARVAGILAP----LIGLL 472

  Fly   521 GWY---IPTTICGCCVLVAGLLTLTLPETGTGKLSDKVESSA--SSTPTE 565
            ..|   ||..|.|....|.|.||..||||....|.|..:..|  |.|.||
Zfish   473 DVYHHAIPMIIYGSLPFVGGALTFLLPETLNTDLQDHTDIPADESMTVTE 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	113/383 (30%)
slc22a13b	XP_017209322.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588862
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.910