DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and oatx

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	532	Identity:	149/532 - (28%)
Similarity:	245/532 - (46%)	Gaps:	79/532 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 CVTPNILNGFHVSSYTLL-GHLPDDQWCGIPE---LQDTNW-------THAQKREIVAKGLDSGG 98
            |..||:....:.|:.||| ..:|.|....:.:   .:||.|       :|....|:..:|...|
Zfish    49 CRIPNVTTAMNDSTTTLLRAFIPLDSSLTLSKCSRYKDTQWHLITDKLSHGNATELQTEGCADG- 112

  Fly    99 CTVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCD-RSI 162
                 |.|                                .:.||.   ::.|::|||.|. |.:
Zfish   113 -----WTY--------------------------------DKSEFI---SSIVSEWDLVCTLRPL 137

  Fly   163 QRTSAQVSISLGKFCGSFSFGILADKFGRK-----SSFTLGAAFFIVGSFFCTFSPWYSLFLAGR 222
            ::.|..:.:. |...|:..||.|:|:||||     |.|.|.    ::|| |...:|.|.::...|
Zfish   138 KQMSQTIYMG-GVLTGAIIFGGLSDRFGRKALLIWSYFQLA----LLGS-FTALAPSYVVYCIFR 196

  Fly   223 FALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGYVIQPWRHLQLALTIP 287
            |..|.:.||:...|.::.||.|..|.|:.:....|..:..|.::||.|.|.::.||.:|:|:.:|
Zfish   197 FLTGMSVSGVILNAVSLKVEWIPTKTRTLVGTLSSFFFTFGQMVLAGVAYSLRDWRKIQMAVCLP 261

  Fly   288 SLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQVASDKKSLEPEEGFSF 352
            ..:..:..:..|||.|||:.|.|.:...|:|.|      :......|..  ::|.:||..|....
Zfish   262 FFIFFMYSWWFSESARWLVLNGRSEEALKLLHR------VAKINGKPEM--TEKITLEELESHMQ 318

  Fly   353 GQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYIIGTGLVDI 417
            .:...:..:.::.:|.....:|::......::..||.:||..|::.....|:.||..:..|.||.
Zfish   319 KEVQSSKSIYTVFDLLRTPTMRKISMCLMVVWFSTSFAYYGLAMDLQKFGVNIYLMQVIFGAVDF 383

  Fly   418 PSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIVAFAMLGRFGISATYSVVTLY 482
            |:.||.::||.|.|||||.....|.:...:...:.||........|.|:||:...||:::.|.|:
Zfish   384 PAKLVALLMLSFLGRRLTQGACLLVSASIIFANIFVPEDMQVTRTALAVLGKGFTSASFTCVYLF 448

  Fly   483 TAELYPTQIRNSALGTCSTFAHVGSISAPYVV---DVLGALGWYIPTTICGCCVLVAGLLTLTLP 544
            |.|||||.||.:.:|..||.:.:||::||.|:   |:|.||    |:.:.|...::|||:...||
Zfish   449 TGELYPTVIRQTGMGFVSTMSRIGSMAAPAVLILDDILPAL----PSIVYGGSAVIAGLIAFLLP 509

  Fly   545 ETGTGKLSDKVE 556
            ||....|.|.::
Zfish   510 ETLNIPLPDTID 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	116/384 (30%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D386678at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.020