DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and Orct

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001262908.1	Gene:	Orct / 42891	FlyBaseID:	FBgn0019952	Length:	548	Species:	Drosophila melanogaster

Alignment Length:	568	Identity:	153/568 - (26%)
Similarity:	262/568 - (46%)	Gaps:	59/568 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 DLLTKQLEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWCGIPELQDTNWTHAQK 86
            |::|.    :|..|.:...|::|...|.|:..||..:...|...||.: |.:|
  Fly     5 DVITH----LGEFGPYQKRIYYLLCLPAIVCAFHKLAGVFLLAKPDFR-CALP------------ 52

  Fly    87 REIVAKGLDSGGC-----TVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHEFAHP 146
                   .::|..     .:|:.:|....:.|| ..::||......|.|.. |...|....:.:.
  Fly    53 -------YENGSIYELSPHLWNLSYPENERCSY-YDVDYTEEYLNGSIPRS-SNETKTCSSYVYD 108

  Fly   147 ETTF----VADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSF 207
            .:.:    |.:|:|.|.||:...::.....||...||..||.::||.|||.:|.......::...
  Fly   109 RSKYLNSAVTEWNLVCSRSLLSATSDSLFMLGVLLGSLIFGQMSDKLGRKPTFFASLVLQLIFGV 173

  Fly   208 FCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGY 272
            ....:|.|..:...|..:||.:||:|..|:.:.:|.:...:|.:..:|....:.||.::.|...|
  Fly   174 LAAVAPEYFSYTISRMIVGATTSGVFLVAYVIALEMVGSSYRLFAGVAMQMFFSVGFMLTAGFAY 238

  Fly   273 VIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKILFRQPSHYQIQPAVAAPSQV 337
            .|..||.||:|:|:|.||.:...:::.||.|||:...|.|..:.|:.:.....:::    .|:::
  Fly   239 FIHDWRWLQIAITLPGLLFLCYYWIIPESARWLLMKGRKDEAFVIIEKAAKENKVE----VPNEI 299

  Fly   338 -------ASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVTA 395
                   .::||..:        :...:.|..::.:|.....:||.....:|.:.|.|..||..:
  Fly   300 YEQLVDEVAEKKKQD--------EMAASQPAATVFDLLRYPNLRRKTLLIFFDWFVNSGVYYGLS 356

  Fly   396 LNAANLSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTW 460
            .|..||..::.:..:.:|.|:||.|.:.:..|...|||.......:..|:|||..:.||:.....
  Fly   357 WNTNNLGGNQLVNFMISGAVEIPGYTLLLFTLNRWGRRSILCGTMMVAGISLLATIFVPSDMNWL 421

  Fly   461 IVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIP 525
            |||.||:|:..|:::|..:.:::||.:||.:||..||..|..|.||.|.||| :.:||.:...:|
  Fly   422 IVACAMIGKLAITSSYGTIYIFSAEQFPTVVRNVGLGASSMVARVGGILAPY-LKLLGEIWRPLP 485

  Fly   526 TTICGCCVLVAGLLTLTLPETGTGKLSDKVESSAS----STPTEPAEK 569
            ..|||...|.||||:|.||||....:.:.:|...:    ..|.|.||:
  Fly   486 LIICGALSLTAGLLSLLLPETLNKPMPETIEDGENFGKKPAPQETAEE 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	112/383 (29%)
Orct	NP_001262908.1	2A0119	11..514	CDD:273328	146/537 (27%)
Orct	NP_001262908.1	MFS	135..491	CDD:119392	105/368 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458323
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D13331at6656
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	8	8.000