DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6356 and CG7342

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_001247196.1	Gene:	CG7342 / 42335	FlyBaseID:	FBgn0038716	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	551	Identity:	122/551 - (22%)
Similarity:	213/551 - (38%)	Gaps:	101/551 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 KQLEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTLLGHLPDDQWC--GIPELQDTNWTHAQKRE 88
            |.||..|........:..|....|:|:..|..|.|::..:| ..||  |:|             .
  Fly     6 KILEKCGDFSRLQMIMLLLFCVINVLSALHYYSQTIISFVP-KYWCADGLP-------------A 56

  Fly    89 IVAKGLDSGGC-----------TVWDWNYGHLAKMSYEAALNYTGHLTQISPPAEVSCRVKGQHE 142
            .:...:|| .|           |.:.:|        ||..:.|.      |.|:|:
  Fly    57 SIESPVDS-SCLPLNRNISTPNTCYSYN--------YELYMGYQ------SFPSEM--------- 97

  Fly   143 FAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSF 207
                      ||  .|..:.:.|..|....:|...||...|.|||..||.....:.....:.|:.
  Fly    98 ----------DW--VCADAWKLTLGQSMFFVGSVVGSMVLGYLADVVGRLPILIVANLIAMTGNL 150

  Fly   208 FCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRS-WMSIAFSASYPVGMIILAIVG 271
            ...:|...:||...|...|.|:...|...:.:::|.:....|: .:||.....|.:|.:....:.
  Fly   151 LTIWSTNVTLFCMFRMISGIATDSNFVMMYILVMEYMRPSVRTLGLSICIGFFYCLGSMAAPWIA 215

  Fly   272 YVIQPWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYD-------RVYKILFRQPSHYQIQP 329
            .:::.||...|..::|.|::.....::.||.:|||:.|:||       ||.||..|....
  Fly   216 VLMRSWRGFLLTTSLPLLVVPFFYLIVPESIQWLISKQKYDSAVVCLKRVAKINGRHVEE----- 275

  Fly   330 AVAAPSQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRMIFASYFMFCVTSLSYYVT 394
              :|.::...:.|..:        |..|..|  .:::|:...::||.....:|...|.:|.|...
  Fly   276 --SAYAEFIEECKCSQ--------QNQKASP--HLLDLFQTPRLRRHTLILFFKSMVITLCYDAV 328

  Fly   395 ALNAANLSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLL----LVLAVPA 455
            :.|...|.:|.::....:....:|:.|:.:.:....||:.......|.:|:.:.    ::.|..|
  Fly   329 SRNVQGLGISPFVMFSLSATAILPACLLIIALQDRIGRKAMASASLLLSGIFISVTGGIIFAASA 393

  Fly   456 G--STTWIVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVV---D 515
            .  :||.:|:.:::||||::..|:....|..||.||.:|...:.......:..:..:.|::   .
  Fly   394 SDKTTTLLVSLSVVGRFGVTVAYNSGAQYATELIPTCVRGQGVAAVHVAGYAFTFFSAYILFTRS 458

  Fly   516 VLGALGWYIPTTICGCCVLVAGLLTLTLPET 546
            |...|    |..|.|...|:...|.|.||||
  Fly   459 VFSPL----PEIILGVLSLLGACLCLLLPET 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	88/393 (22%)
CG7342	NP_001247196.1	2A0119	12..491	CDD:273328	119/545 (22%)
CG7342	NP_001247196.1	MFS	93..>243	CDD:119392	35/170 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458478
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	6	5.990