Protein Alignment CG6356 and SLC22A

DIOPT Version :10

• Sequence 1: NP_651240.1
• Gene: CG6356 / 42893
• FlyBaseID: FBgn0039178
• Length: 570
• Species: Drosophila melanogaster
• Sequence 2: NP_649370.1
• Gene: SLC22A / 40437
• FlyBaseID: FBgn0037140
• Length: 568
• Species: Drosophila melanogaster
• Alignment Length: 575
• Identity: 149/575 - (25%)
• Similarity: 234/575 - (40%)
• Gaps: 72/575 - (12%)

  Fly     8 PEKNRELISEESMKDLLTKQLEVVGSGGAFVWAIFFLCVTPNILNGFHVSSYTL----LGHLPDD 68
            |.|:    ||:...|.:.|.|   |..|.|...||.|...|.:.:.....:|..    :.|....
  Fly    18 PAKD----SEDVTLDAILKHL---GQFGRFQLIIFLLICLPMMFHAMFSVTYVFTAATVTHRCSV 75

  Fly    69 QWCGIPELQ----DTNWTHAQKREIVAKGLDSGGCTVW------DWNYG-------HLAKMSYEA 116
            :.|.:|...    .|||:      |...|.|...|..:      .||:.       |..|.....
  Fly    76 EECDLPGSNYYEPHTNWS------IPKNGKDLDSCNRYTNSELPQWNHSVDICSADHFTKNKEAC 134

  Fly   117 ALNYTGHLTQISPPAEVSCRVKGQHEFAHPETTFVADWDLTCDRSIQRTSAQVSISLGKFCGSFS 181
            |.|                    :..|...|.|...|:.:.||...:.:......:||:|.|...
  Fly   135 AHN--------------------EFVFRDDEVTISNDFGIFCDDEWKLSMVGTINNLGQFFGIPI 179

  Fly   182 FGILADKFGRKSSFTLGAAFFIVGSFFCTFSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICL 246
            .|.:||::||..|..||.....|.....:|||.|..||...|.....||.|:...|.:.:|.:..
  Fly   180 GGFVADRYGRSFSIALGGILGAVLGVIRSFSPSYGWFLVFEFLDNMTSSTLYSTCFVIGIELVGP 244

  Fly   247 KHRSWMSIAFSASYPVGMIILAIVGYVIQPWRHLQLALTI-PSLLLILNCYLMSESPRWLITNQR 310
            |.|.......:..|.||.::||:.......||.| |.:|. |||:|:...:::.||.|||::..:
  Fly   245 KRRVLACSVITVFYAVGEVLLAMSAKAFHDWRIL-LRITYGPSLILLAYFWILPESVRWLLSQGK 308

  Fly   311 YDRVYKILFRQPSHYQIQ--PAVAAPSQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKV 373
            .:|...|| |:.:|...:  |.......|.:::..|:......|       |::   |.:.|.|.
  Fly   309 EERAKNIL-RRAAHVNKRELPESVLDKLVLANRDKLQQSSESRF-------PIR---EAFKNFKW 362

  Fly   374 RRMIFASYFMFCVTSLSYYVTALNAANLSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMF 438
            |  |......:.|..|.||..:||...|...:|.......||:||.:.:|::::...|||.:...
  Fly   363 R--IANCSLCWIVHVLVYYGLSLNVVLLDGDKYNNFAYIALVEIPGFFMPLLIMDRFGRRYSLCG 425

  Fly   439 LFLWTGVSLLLVLAVPAGSTTWIVAFAMLGRFGISATYSVVTLYTAELYPTQIRNSALGTCSTFA 503
            |.|.:|:..:..:...|......:...::|:..|:|::.|:..:.:|:|||.:|||.|..||...
  Fly   426 LMLASGLCCIGTIFTGADQPVLQLVLFLVGKLTITASFQVLYFFASEIYPTNLRNSLLSFCSMMG 490

  Fly   504 HVGSISAPYVVDVLGALGWYIPTTICGCCVLVAGLLTLTLPETGTGKLSDKVESS 558
            ..||:.||. ..:|.......|..:.....:|:|||||..|||....|...|:.:
  Fly   491 RFGSMLAPQ-TPLLAKYYANAPAMLFAGAAIVSGLLTLFFPETTNVVLPTTVQEA 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS_SLC22	140..544	CDD:340875	113/406 (28%)
SLC22A	NP_649370.1	MFS_SLC22	136..530	CDD:340875	114/428 (27%)