DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6356 and slc22a7b.1

DIOPT Version :9

Sequence 1:	NP_651240.1	Gene:	CG6356 / 42893	FlyBaseID:	FBgn0039178	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	XP_021322800.1	Gene:	slc22a7b.1 / 393320	ZFINID:	ZDB-GENE-040426-1311	Length:	560	Species:	Danio rerio

Alignment Length:	485	Identity:	135/485 - (27%)
Similarity:	228/485 - (47%)	Gaps:	76/485 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 GHLTQ-----ISPPAE-----VSCRVKGQHEFAHPE--------------------------TTF 150
            |:|||     :|.||:     .||     |.||||:                          :||
Zfish    70 GNLTQKERLIVSVPAQEDGTPASC-----HMFAHPQFQLLINSSSSSALPVVECQNGWHFDNSTF 129

  Fly   151 VA----DWDLTCD-RSIQRTSAQVSISLGKFCGSFSFGILADKFGRKSSFTLGAAFFIVGSFFCT 210
            ::    .:||.|| |.:.:.||.: ..:|..||:..||:|.||:||:|...:...|.||.|....
Zfish   130 ISTLATQFDLVCDKRGLAKASATI-FFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSVTSA 193

  Fly   211 FSPWYSLFLAGRFALGAASSGLFYPAFTMIVENICLKHRSWMSIAFSASYPVGMIILAIVGYVIQ 275
            ||..|.:|.|.||..|.|.:|:...:..:.:|.:..|||::|.:..|.|:.:|.::||...:::.
Zfish   194 FSSSYIMFAAFRFLTGLALTGISNISVVLSIEWVDTKHRTFMGLFGSMSWSIGNMLLAGFAFMVT 258

  Fly   276 PWRHLQLALTIPSLLLILNCYLMSESPRWLITNQRYDRVYKIL-----FRQPSHY--QIQPAVAA 333
            .||.|.:.:|.|..|.....:.:.:|.||||.|.:.:..||.|     |.|...:  :::|...:
Zfish   259 DWRLLIVIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNQRLDFTSRVKPETLS 323

  Fly   334 PSQVASDKKSLEPEEGFSFGQKLKNGPLKSIIELYANSKVRRM-IFASYFMFCVTSLSYYVTALN 397
             :.|..|.:      |.|:          :.::|....::|:: :|.....:.|.| :||..:||
Zfish   324 -TVVTVDHR------GHSY----------TYLDLVKTPQLRKLTLFTGIVWYGVAS-TYYGISLN 370

  Fly   398 AANLSVSRYLYIIGTGLVDIPSYLVPVIMLRFTGRRLTTMFLFLWTGVSLLLVLAVPAGSTTWIV 462
            .....:..||.......:::|:.::....|...|||.|.....:.||..:|:.:..|....|:..
Zfish   371 ITGFGLDPYLTHFIYAAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILINIITPTEYWTFRT 435

  Fly   463 AFAMLGRFGIS-ATYSVVTLYTAELYPTQIRNSALGTCSTFAHVGSISAPYVVDVLGALGWYIPT 526
            ..|:||: |:| |:::.|.|||.|||||.:|.:.||..:..|.:|:..:|.:: :|..:...:|.
Zfish   436 VIAVLGK-GLSEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIM-LLEDIWKLLPE 498

  Fly   527 TICGCCVLVAGLLTLTLPETGTGKLSDKVE 556
            .|.....:..|::.|.||||....|.:.||
Zfish   499 VIFCSMAIFCGIIALLLPETNNASLPETVE 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6356	NP_651240.1	MFS	167..544	CDD:119392	106/385 (28%)
slc22a7b.1	XP_021322800.1	Sugar_tr	22..526	CDD:331684	133/481 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170588946
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.940